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UK Dementia Trials Network: an expert‐informed framework for improving representation in dementia trials

by Clinical Neuropsychologist Online | Monday, October 26, 2026 | Dementia

Abstract Alzheimer’s disease (AD) is the leading cause of dementia worldwide, yet clinical trials remain unrepresentative of those most affected. Ethnic minoritized groups, socioeconomically deprived communities, adults over 75, and populations in low- and...

Correction to Alzheimer’s & dementia articles

by Clinical Neuropsychologist Online | Monday, October 26, 2026 | Dementia

Alzheimer’s &Dementia, Volume 22, Issue 10, October 2026. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: | October 26, 2026 Neuro-Dementia...

Neuropathologic features of cognitively defined Alzheimer’s disease subgroups in the Adult Changes in Thought study

by Clinical Neuropsychologist Online | Monday, October 26, 2026 | Dementia

Abstract BACKGROUND Individuals with Alzheimer’s disease (AD) dementia can be subgrouped based on cognitive performance at diagnosis. We compared neuropathology across cognitively defined AD subgroups in the Adult Changes in Thought study. METHODS Scores for...

α‐synuclein pathology drives region‐specific tau deposition

by Clinical Neuropsychologist Online | Monday, October 26, 2026 | Dementia

Abstract INTRODUCTION Dementia with Lewy bodies (DLB) is a common but underdiagnosed neurodegenerative disease associated with α-synuclein pathology. Clinically, DLB is characterized by early motor dysfunction and psychiatric symptoms, in contrast to early memory...

Why sleep assessment belongs in the memory clinic

by Clinical Neuropsychologist Online | Monday, October 26, 2026 | Dementia

Abstract Sleep disturbances are highly prevalent in older adults and are particularly common among individuals attending memory clinics for assessment of cognitive impairment. Emerging evidence links sleep disorders, including insomnia, obstructive sleep apnea,...

Tau extent is associated with lower cognition in Down syndrome‐related Alzheimer’s disease

by Clinical Neuropsychologist Online | Sunday, October 25, 2026 | Dementia

Abstract INTRODUCTION 18F-MK6240 is a second-generation tau positron emission tomography (PET) tracer with high dynamic range able to detect early tau pathology in Alzheimer’s disease, however, its binding characteristics have not been evaluated in Down syndrome...
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