by Clinical Neuropsychologist | Thursday, March 20, 2025 | Dementia
Abstract INTRODUCTION Marital status is a potential risk/protective factor for adverse health outcomes. This study tested whether marital status was associated with dementia risk in older adults. METHODS Participants (N = 24,107; Meanage = 71.79) were from the...
by Clinical Neuropsychologist | Thursday, March 20, 2025 | Dementia
Abstract INTRODUCTION Metabolic stressors (obesity, metabolic syndrome, prediabetes, and type 2 diabetes [T2D]) increase the risk of cognitive impairment (CI), including Alzheimer’s disease (AD). Immune system dysregulation and inflammation, particularly...
by Clinical Neuropsychologist | Thursday, March 20, 2025 | Dementia
Abstract INTRODUCTION Autosomal dominant Alzheimer’s disease (ADAD) through genetic mutations can result in near complete expression of the disease. Tracking AD pathology development in an ADAD cohort of Presenilin-1 (PSEN1) E280A carriers’ mutation has allowed...
by Clinical Neuropsychologist | Thursday, March 20, 2025 | Dementia
Abstract INTRODUCTION Accelerated long-term forgetting (LTF) might be an early marker of subtle memory changes in older adults at risk for Alzheimer’s disease (AD). We leveraged remote, multi-day digital testing to characterize LTF in older adults and...
by Clinical Neuropsychologist | Thursday, March 20, 2025 | Dementia
Abstract INTRODUCTION Alzheimer’s disease (AD) is characterized by amyloid pathology and neuroinflammation, leading to cognitive decline. Targeting histone deacetylase-11 (HDAC11) offers a novel therapeutic strategy due to its role in immune regulation. METHODS...
by Clinical Neuropsychologist | Thursday, March 20, 2025 | Dementia
Abstract Interventions addressing modifiable personal and environmental factors are critical to optimize dementia mealtime care, caregiving, and outcomes. This review synthesized the characteristics and effects of non-pharmacological interventions on mealtime care and...
