by Clinical Neuropsychologist | Thursday, December 19, 2024 | Dementia
Abstract INTRODUCTION While there may be microbial contributions to Alzheimer’s disease (AD), findings have been inconclusive. We recently reported an AD-associated CD83(+) microglia subtype associated with increased immunoglobulin G4 (IgG4) in the transverse...
by Clinical Neuropsychologist | Thursday, December 19, 2024 | Dementia
Abstract INTRODUCTION Cerebrovascular dysfunction occurs in Alzheimer’s disease (AD), impairing hemodynamic regulation. Large conductance Ca2+-activated K+ channels (BKCa) regulate cerebrovascular reactivity and are impaired in AD. BKCa activity depends on...
by Clinical Neuropsychologist | Thursday, December 19, 2024 | Dementia
Abstract To understand the potential benefits of emerging Alzheimer’s disease (AD) therapies within and beyond clinical trial settings, there is a need to advance current outcome measurements into meaningful information relevant to all stakeholders. The...
by Clinical Neuropsychologist | Wednesday, December 18, 2024 | Dementia
Abstract The immune system is a key player in the onset and progression of neurodegenerative disorders. While brain resident immune cell-mediated neuroinflammation and peripheral immune cell (eg, T cell) infiltration into the brain have been shown to significantly...
by Clinical Neuropsychologist | Wednesday, December 18, 2024 | Dementia
Abstract INTRODUCTION Studies using cross-sectional data or with a short follow-up period fail to distinguish whether the associations between sleep duration and physical activity with cognitive function result from reverse causation. METHODS The longitudinal study...
by Clinical Neuropsychologist | Wednesday, December 18, 2024 | Dementia
Alzheimer’s &Dementia, EarlyView. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: Claire J. Lansdall, Jeffrey L. Cummings, Jeffrey Scott Andrews...
