The multiple scales of astrocytic functional units

by Clinical Neuropsychologist Online | Wednesday, May 27, 2026 | Neuroscience

Nature Neuroscience, Published online: 27 May 2026; doi:10.1038/s41593-026-02308-xAstrocytes modulate complex brain functions. These ubiquitous glial cells constitute a multilayered system of functional units that operate across multiple spatial scales, thereby...

Microglial mitochondria transfer to astrocytes via GPNMB-enriched extracellular vesicles alleviates cognitive deficits in tauopathy mice

by Clinical Neuropsychologist Online | Tuesday, May 26, 2026 | Neuroscience

Nature Neuroscience, Published online: 26 May 2026; doi:10.1038/s41593-026-02317-wIn PS19 mice, microglia-derived glycoprotein nonmetastatic melanoma protein B promotes mitochondrial extracellular vesicle secretion, enabling mitochondrial transfer to astrocytes. This...

Fixation duration on natural scenes is explained by memory encoding not processing demand

by Clinical Neuropsychologist Online | Monday, May 25, 2026 | Neuroscience

Nature Neuroscience, Published online: 25 May 2026; doi:10.1038/s41593-026-02285-1By combining magnetoencephalography and eye tracking, this study sheds light on why people fixate on some parts of natural scenes longer than others. Rather than visual complexity,...

Low-dimensional population dynamics in the brainstem gate REM sleep

by Clinical Neuropsychologist Online | Monday, May 25, 2026 | Neuroscience

Nature Neuroscience, Published online: 25 May 2026; doi:10.1038/s41593-026-02314-zLozano et al. show that REM sleep is gated by low-dimensional brainstem network dynamics, in which opposing neuron populations across the midbrain and pons determine when transitions...

Foamy microglia link oxylipins to disease progression in multiple sclerosis

by Clinical Neuropsychologist Online | Thursday, May 21, 2026 | Neuroscience

Nature Neuroscience, Published online: 21 May 2026; doi:10.1038/s41593-026-02302-3Foamy microglia are associated with multiple sclerosis progression, linking phagocytosis, altered lipid metabolism (oxylipins) and lysosomal stress to nonclassical neuroinflammation and...

Why Brain Lipids Matter: The Hidden Players in Brain Health

by Clinical Neuropsychologist Online | Wednesday, May 20, 2026 | Neuroscience

Migraine – a particular type of headache that can come with visual, sensory, and other symptoms—; strikes one in seven people worldwide. Researchers believe that migraine symptoms are caused by ;neurogenic ;inflammation along with vascular changes in the brain, but...