Strong and localized recurrence controls the dimensionality of neural activity across brain areas

by Clinical Neuropsychologist Online | Wednesday, August 19, 2026 | Neuroscience

Nature Neuroscience, Published online: 19 August 2026; doi:10.1038/s41593-026-02395-wBrain activity is complex but not arbitrary, and some patterns dominate others, with dimensionality describing how many such patterns exist. The authors show how brain connectivity...

Cortical thickness changes precede high levels of amyloid by at least 7 years

by Clinical Neuropsychologist Online | Wednesday, August 19, 2026 | Neuroscience

Nature Neuroscience, Published online: 19 August 2026; doi:10.1038/s41593-026-02363-4Longitudinal MRI reveals that the cortex becomes relatively thicker years before amyloid positivity is detected on PET, providing insight into the earliest brain changes and potential...

Microglia activation by derepression of endogenous retroviruses drives inflammation and cellular senescence

by Clinical Neuropsychologist Online | Monday, August 17, 2026 | Neuroscience

Nature Neuroscience, Published online: 17 August 2026; doi:10.1038/s41593-026-02404-yReawakening of endogenous retroviruses due to loss of chromatin compaction causes microglia to acquire aging-associated features, leading to perturbed tissue homeostasis and behavior....

Reusable modular architecture enables flexible cognitive operations in the mouse brain and artificial recurrent networks

by Clinical Neuropsychologist Online | Monday, August 17, 2026 | Neuroscience

Nature Neuroscience, Published online: 17 August 2026; doi:10.1038/s41593-026-02410-0Mice flexibly reuse neurons specialized for stimulus processing and memory maintenance, regardless of the content, providing evidence for reusable modular organization in the brain....

Dendritic translation and neuroproteasome-mediated degradation of endogenous tau revealed by STARFISH

by Clinical Neuropsychologist Online | Thursday, August 13, 2026 | Neuroscience

Nature Neuroscience, Published online: 13 August 2026; doi:10.1038/s41593-026-02398-7STARFISH, a method for visualizing endogenous mRNA translation, is used to show that tau is translated exclusively in neuronal dendrites and rapidly degraded by neuroproteasomes....

Cross-region neuron co-firing mediated by ripple oscillations supports distributed working memory representations

by Clinical Neuropsychologist Online | Wednesday, August 12, 2026 | Neuroscience

Nature Neuroscience, Published online: 12 August 2026; doi:10.1038/s41593-026-02403-zThe authors show that human neurons in bilateral corticolimbic sites fire together, modulated by working memory, and reinstate stimulus-selective firings when both sites briefly...