Mitochondrial stress response drives microglial senescence

by Clinical Neuropsychologist Online | Friday, June 26, 2026 | Neuroscience

Nature Neuroscience, Published online: 26 June 2026; doi:10.1038/s41593-026-02264-6The mitochondrial unfolded protein response (UPRmt) drives microglial senescence and disrupts essential glia–neuron communication. By triggering lipid droplet accumulation and...

Human hippocampal ripples tune cortical responses based on predicted uncertainty

by Clinical Neuropsychologist Online | Thursday, June 25, 2026 | Neuroscience

Nature Neuroscience, Published online: 25 June 2026; doi:10.1038/s41593-026-02345-6Using direct recordings from the human brain, Frank et al. show that hippocampal ripples increase ahead of unpredictable events and tune the visual cortex to respond faster and more...

Learning shapes neural geometry in the primate prefrontal cortex

by Clinical Neuropsychologist Online | Thursday, June 25, 2026 | Neuroscience

Nature Neuroscience, Published online: 25 June 2026; doi:10.1038/s41593-026-02333-wLearning transforms prefrontal cortex activity from flexible, high-dimensional representations into compact, task-relevant and abstract codes, enabling efficient generalization of...

DBS: from neuromodulation to neuroremodelling

by Clinical Neuropsychologist Online | Thursday, June 25, 2026 | Neuroscience

Nature Neuroscience, Published online: 25 June 2026; doi:10.1038/s41593-026-02347-4Deep-brain stimulation (DBS) treats movement and neuropsychiatric disorders through mechanisms that remain unclear. Two studies that combine longitudinal neuroimaging, stimulation...

Cell atlas of brain aneurysms reveals fibroblast–macrophage crosstalk

by Clinical Neuropsychologist Online | Wednesday, June 24, 2026 | Neuroscience

Nature Neuroscience, Published online: 24 June 2026; doi:10.1038/s41593-026-02368-zBrain aneurysms are a major cause of stroke worldwide, yet the cellular mechanisms that drive vessel instability remain poorly defined. A combined single-cell and spatial transcriptomic...

Author Correction: Cerebellar aging is spatially heterogeneous and supports cognitive resilience in later life

by Clinical Neuropsychologist Online | Tuesday, June 23, 2026 | Neuroscience

Nature Neuroscience, Published online: 23 June 2026; doi:10.1038/s41593-026-02374-1Author Correction: Cerebellar aging is spatially heterogeneous and supports cognitive resilience in later life If you do not see content above, kindly GO TO SOURCE. Not all publishers...