Deep RNA sequencing of human dorsal root ganglion neurons reveals somatosensory mechanisms

by Clinical Neuropsychologist | Wednesday, November 6, 2024 | Neuroscience

Nature Neuroscience, Published online: 06 November 2024; doi:10.1038/s41593-024-01795-0We used single-soma deep RNA sequencing to generate a high-resolution atlas of human somatosensory dorsal root ganglion neurons. This work revealed human-specific molecular...

Spatially resolved gene signatures of white matter lesion progression in multiple sclerosis

by Clinical Neuropsychologist | Tuesday, November 5, 2024 | Neuroscience

Nature Neuroscience, Published online: 05 November 2024; doi:10.1038/s41593-024-01765-6Lesion initiation and progression in multiple sclerosis is a dynamic but unclear process. Here, the authors highlight cell type-specific gene sets characterizing the action lesion...

Cell type mapping reveals tissue niches and interactions in subcortical multiple sclerosis lesions

by Clinical Neuropsychologist | Tuesday, November 5, 2024 | Neuroscience

Nature Neuroscience, Published online: 05 November 2024; doi:10.1038/s41593-024-01796-zLerma-Martin et al. generated a paired single-nucleus RNA sequencing and spatial transcriptomics dataset from subcortical multiple sclerosis lesions, identifying spatial niches and...

Mapping out multiple sclerosis with spatial transcriptomics

by Clinical Neuropsychologist | Tuesday, November 5, 2024 | Neuroscience

Nature Neuroscience, Published online: 05 November 2024; doi:10.1038/s41593-024-01798-xIn this issue, Alsema, Wijering, Miedema, Kotah et al. and Lerma-Martin, Badia-i-Mompel et al. demonstrate the ever-growing possibilities of spatial transcriptomics by applying it...

Astrocytes facilitate brain metastases

by Clinical Neuropsychologist | Monday, November 4, 2024 | Neuroscience

Nature Neuroscience, Published online: 04 November 2024; doi:10.1038/s41593-024-01805-1Astrocytes facilitate brain metastases If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This...

Alcohol’s necessary accessory

by Clinical Neuropsychologist | Monday, November 4, 2024 | Neuroscience

Nature Neuroscience, Published online: 04 November 2024; doi:10.1038/s41593-024-01802-4Alcohol’s necessary accessory If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is...