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CT1812 biomarker signature from a meta‐analysis of CSF proteomic findings from two Phase 2 clinical trials in Alzheimer’s disease

by Clinical Neuropsychologist Online | Wednesday, August 21, 2024 | Dementia

Abstract INTRODUCTION CT1812 is in clinical development for the treatment of Alzheimer’s disease (AD). Cerebrospinal fluid (CSF) exploratory proteomics was employed to identify pharmacodynamic biomarkers of CT1812 in mild to moderate AD from two independent...

The relationship between adult hippocampal neurogenesis and cognitive impairment in Alzheimer’s disease

by Clinical Neuropsychologist Online | Wednesday, August 21, 2024 | Dementia

Abstract Neurogenesis persists throughout adulthood in the hippocampus and contributes to specific cognitive functions. In Alzheimer’s disease (AD), the hippocampus is affected by pathology and functional impairment early in the disease. Human AD patients have...

“Make research more people‐centered”: Two ADNI participants share recommendations for more inclusive Alzheimer’s disease research

by Clinical Neuropsychologist Online | Wednesday, August 21, 2024 | Dementia

Alzheimer’s &Dementia, EarlyView. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: Sarah Walter, Rochelle Long, Cynthia Huling Hummel | August 21,...

Real-world occupational therapy interventions for early-stage dementia: Characteristics and contextual barriers

by Clinical Neuropsychologist Online | Tuesday, August 20, 2024 | Dementia

Dementia, Volume 24, Issue 3, Page 388-407, April 2025. AimThere is an absence of evidence generated in a UK context to support interventions based on occupational therapists’ core skills for people living with early-stage dementia. To inform the development of a...

Understanding dementia in minority ethnic communities: The perspectives of key stakeholders interviewed as part of the IDEAL programme

by Clinical Neuropsychologist Online | Saturday, August 17, 2024 | Dementia

Dementia, Volume 23, Issue 7, Page 1172-1182, October 2024. Future populations of older adults in the UK, those aged 65+, will demonstrate increased diversity in terms of their ethnic identity resultant from the ageing of the post-war migrants from India, Pakistan,...
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