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Considerations for widespread implementation of blood‐based biomarkers of Alzheimer’s disease

by Clinical Neuropsychologist Online | Sunday, October 6, 2024 | Dementia

Abstract Diagnosing Alzheimer’s disease (AD) poses significant challenges to health care, often resulting in delayed or inadequate patient care. The clinical integration of blood-based biomarkers (BBMs) for AD holds promise in enabling early detection of...

Brexpiprazole treatment for agitation in Alzheimer’s dementia: A randomized study

by Clinical Neuropsychologist Online | Sunday, October 6, 2024 | Dementia

Abstract INTRODUCTION We evaluated the efficacy and safety of brexpiprazole for the treatment of agitation in Alzheimer’s dementia (AAD) in Japanese patients. METHODS This was a phase 2/3 multicenter, randomized, double-blind, placebo-controlled, parallel-group...

Need to adapt Alzheimer’s disease criteria in Latin America

by Clinical Neuropsychologist Online | Sunday, October 6, 2024 | Dementia

Alzheimer’s &Dementia, EarlyView. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: Nilton Custodio, Ricardo Allegri, Francisco Lopera, Paulo...

Plasma and CSF neurofilament light chain distinguish neurodegenerative from primary psychiatric conditions in a clinical setting

by Clinical Neuropsychologist Online | Sunday, October 6, 2024 | Dementia

Abstract INTRODUCTION People with neurodegenerative disorders (ND) frequently face diagnostic delay and misdiagnosis. We investigated blood and cerebrospinal fluid (CSF) neurofilament light chain (NfL) to distinguish ND from primary psychiatric disorders (PPD), a...

Argentina–Alzheimer’s Disease Neuroimaging Initiative: pioneering Alzheimer’s Research in Latin America and its Implications for Regional Advancement

by Clinical Neuropsychologist Online | Sunday, October 6, 2024 | Dementia

Abstract The Alzheimer’s Disease Neuroimaging Initiative (ADNI) has fostered collaboration among researchers around the world, catalyzing innovation and accelerating progress in the field. In Latin America, this initiative advanced the validation and development...
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