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A genome‐wide association meta‐analysis of all‐cause and vascular dementia

by Clinical Neuropsychologist | Wednesday, July 24, 2024 | Dementia

Abstract INTRODUCTION Dementia is a multifactorial disease with Alzheimer’s disease (AD) and vascular dementia (VaD) pathologies making the largest contributions. Yet, most genome-wide association studies (GWAS) focus on AD. METHODS We conducted a GWAS of...

How are nature-based interventions defined in mild cognitive impairment and dementia studies? A conceptual systematic review and novel taxonomy

by Clinical Neuropsychologist | Wednesday, July 24, 2024 | Dementia

Dementia, Volume 24, Issue 3, Page 480-505, April 2025. ObjectivesTo systematically review research testing nature-based interventions for people living with mild cognitive impairment or dementia, and to report how authors have defined their interventions by...

Harmonizing tau positron emission tomography in Alzheimer’s disease: The CenTauR scale and the joint propagation model

by Clinical Neuropsychologist | Tuesday, July 23, 2024 | Dementia

Abstract INTRODUCTION Tau-positron emission tomography (PET) outcome data of patients with Alzheimer’s disease (AD) cannot currently be meaningfully compared or combined when different tracers are used due to differences in tracer properties, instrumentation,...

Predicting continuous amyloid PET values with CSF tau phosphorylation occupancies

by Clinical Neuropsychologist | Tuesday, July 23, 2024 | Dementia

Abstract INTRODUCTION Cerebrospinal fluid (CSF) tau phosphorylation at multiple sites is associated with cortical amyloid and other pathologic changes in Alzheimer’s disease. These relationships can be non-linear. We used an artificial neural network to assess...

Reasons for undergoing amyloid imaging among diverse enrollees in the A4 study

by Clinical Neuropsychologist | Tuesday, July 23, 2024 | Dementia

Abstract INTRODUCTION Understanding attitudes toward participation among diverse preclinical Alzheimer’s disease (AD) trial participants could yield insights to instruct future recruitment. METHODS Using data from the Anti-Amyloid Treatment in Asymptomatic AD...
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