by Clinical Neuropsychologist Online | Friday, September 6, 2024 | Dementia
Abstract BACKGROUND Digital cognitive assessments, particularly those that can be done at home, present as low-burden biomarkers for participants and patients alike, but their effectiveness in the diagnosis of Alzheimer’s disease (AD) or predicting its...
by Clinical Neuropsychologist Online | Friday, September 6, 2024 | Dementia
Abstract BACKGROUND The Mnemonic Similarity Task (MST) is a popular memory task designed to assess hippocampal integrity. We assessed whether analyzing MST performance using a multinomial processing tree (MPT) cognitive model could detect individuals with elevated...
by Clinical Neuropsychologist Online | Thursday, September 5, 2024 | Dementia
Abstract INTRODUCTION Neuroanatomical normative modeling captures individual variability in Alzheimer’s disease (AD). Here we used normative modeling to track individuals’ disease progression in people with mild cognitive impairment (MCI) and patients with AD....
by Clinical Neuropsychologist Online | Thursday, September 5, 2024 | Dementia
Abstract INTRODUCTION Loneliness has a rising public health impact, but research involving neuropathology and representative cohorts has been limited. METHODS Inverse odds of selection weights were generalized from the autopsy sample of Rush Alzheimer’s Disease...
by Clinical Neuropsychologist Online | Wednesday, September 4, 2024 | Dementia
Abstract BACKGROUND The number of people with dementia is increasing in Japan, and establishing evidence for preventing dementia is necessary. METHODS This study was a randomized controlled trial in cognitively normal community-dwelling older adults aged 65 to 85 with...
