by Clinical Neuropsychologist Online | Wednesday, July 3, 2024 | Dementia
Abstract INTRODUCTION Cerebral blood flow (CBF) is reduced in cognitively impaired (CI) Alzheimer’s disease (AD) patients. We checked the sensitivity of time-encoded arterial spin labeling (te-ASL) in measuring CBF alterations in individuals with positive AD...
by Clinical Neuropsychologist Online | Wednesday, July 3, 2024 | Dementia
Abstract INTRODUCTION Mild cognitive impairment (MCI) is a prodromal stage of dementia. Understanding the mechanistic changes from healthy aging to MCI is critical for comprehending disease progression and enabling preventative intervention. METHODS Patients with MCI...
by Clinical Neuropsychologist Online | Wednesday, July 3, 2024 | Dementia
Abstract INTRODUCTION We examined the burden of neuropsychiatric symptoms (NPSs) in early-onset (EO) and late-onset (LO) Alzheimer’s disease (AD) and adjusted for age effects via the inclusion of cognitively unimpaired (CU) individuals. METHODS Cross-sectional...
by Clinical Neuropsychologist Online | Wednesday, July 3, 2024 | Dementia
Abstract INTRODUCTION Sodium-glucose cotransporter 2 (SGLT2) inhibitors exhibit potential benefits in reducing dementia risk, yet the optimal beneficiary subgroups remain uncertain. METHODS Individuals with type 2 diabetes (T2D) initiating either SGLT2 inhibitor or...
by Clinical Neuropsychologist Online | Wednesday, July 3, 2024 | Dementia
Abstract INTRODUCTION Despite a two-fold risk, individuals of African ancestry have been underrepresented in Alzheimer’s disease (AD) genomics efforts. METHODS Genome-wide association studies (GWAS) of 2,903 AD cases and 6,265 controls of African ancestry....
