by Clinical Neuropsychologist Online | Wednesday, July 3, 2024 | Dementia
Abstract INTRODUCTION We examined the burden of neuropsychiatric symptoms (NPSs) in early-onset (EO) and late-onset (LO) Alzheimer’s disease (AD) and adjusted for age effects via the inclusion of cognitively unimpaired (CU) individuals. METHODS Cross-sectional...
by Clinical Neuropsychologist Online | Wednesday, July 3, 2024 | Dementia
Abstract INTRODUCTION Sodium-glucose cotransporter 2 (SGLT2) inhibitors exhibit potential benefits in reducing dementia risk, yet the optimal beneficiary subgroups remain uncertain. METHODS Individuals with type 2 diabetes (T2D) initiating either SGLT2 inhibitor or...
by Clinical Neuropsychologist Online | Wednesday, July 3, 2024 | Dementia
Abstract INTRODUCTION Despite a two-fold risk, individuals of African ancestry have been underrepresented in Alzheimer’s disease (AD) genomics efforts. METHODS Genome-wide association studies (GWAS) of 2,903 AD cases and 6,265 controls of African ancestry....
by Clinical Neuropsychologist Online | Tuesday, July 2, 2024 | Dementia
Abstract INTRODUCTION Vascular contributions to cognitive impairment and dementia (VCID) represent a major factor in cognitive decline in older adults. The present study examined the relationship between cerebrovascular reactivity (CVR) measured by magnetic resonance...
by Clinical Neuropsychologist Online | Monday, July 1, 2024 | Dementia
Abstract INTRODUCTION Although reproductive hormones are implicated in cerebral small vessel disease in women, few studies consider measured hormones in relation to white matter hyperintensity volume (WMHV), a key indicator of cerebral small vessel disease. Even fewer...
