by Clinical Neuropsychologist | Wednesday, September 11, 2024 | Dementia
Abstract The magnetic resonance imaging (MRI) Core has been operating since Alzheimer’s Disease Neuroimaging Initiative’s (ADNI) inception, providing 20 years of data including reliable, multi-platform standardized protocols, carefully curated image data,...
by Clinical Neuropsychologist | Tuesday, September 10, 2024 | Dementia
Abstract INTRODUCTION Frontotemporal dementia (FTD) is characterized by phenotypic and genetic heterogeneities. However, reports on the large Chinese FTD cohort are lacking. METHODS Two hundred forty-eight patients with FTD were enrolled. All patients and 2010 healthy...
by Clinical Neuropsychologist | Tuesday, September 10, 2024 | Dementia
Abstract INTRODUCTION Few studies have examined the relationship between education and cognition among the oldest–old. METHODS Cognitive assessments were conducted biannually for 803 participants (62.6% women) of LifeAfter90, a longitudinal study of individuals ≥ 90...
by Clinical Neuropsychologist | Tuesday, September 10, 2024 | Dementia
Abstract INTRODUCTION We investigated distinctive factors associated with cognitive reserve (CR) based on education level. METHODS Among 1247 participants who underwent neuropsychological assessment, amyloid positron emission tomography, and brain magnetic resonance...
by Clinical Neuropsychologist | Tuesday, September 10, 2024 | Dementia
Abstract INTRODUCTION We investigated the interactive associations between amyloid and hypertension on the entorhinal cortex (EC) tau and atrophy and the role of cerebral blood flow (CBF) as a shared mechanism by which amyloid and hypertension contribute to EC tau and...