by Clinical Neuropsychologist Online | Saturday, June 15, 2024 | Dementia
Abstract INTRODUCTION TAR DNA-binding protein 43 (TDP-43) is a highly prevalent proteinopathy that is involved in neurodegenerative processes, including axonal damage. To date, no ante mortem biomarkers exist for TDP-43, and few studies have directly assessed its...
by Clinical Neuropsychologist Online | Saturday, June 15, 2024 | Dementia
Abstract INTRODUCTION The contribution of neuropsychological assessments to risk assessment for incident dementia is underappreciated. METHODS We analyzed neuropsychological testing results in dementia-free participants in the Atherosclerosis Risk in Communities...
by Clinical Neuropsychologist Online | Saturday, June 15, 2024 | Dementia
Abstract BACKGROUND The mechanisms linking mild behavioral impairment (MBI) and Alzheimer’s disease (AD) have been insufficiently explored, with conflicting results regarding tau protein and few data on other metabolic markers. We aimed to evaluate the...
by Clinical Neuropsychologist Online | Saturday, June 15, 2024 | Dementia
Abstract INTRODUCTION The entorhinal cortex (EC) and perirhinal cortex (PC) are vulnerable to Alzheimer’s disease. A triggering factor may be the interaction of vascular dysfunction and tau pathology. METHODS We imaged post mortem human tissue at 100 μm3 with 7...
by Clinical Neuropsychologist Online | Friday, June 14, 2024 | Dementia
Abstract INTRODUCTION Poor social connection is considered a risk factor for dementia. Since socializing behaviors may cluster together or act compensatorily, we aimed to investigate social connection patterns and their association with dementia, for men and women...
