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Overrepresentation of APOE ε4 carriers in genome‐wide association studies of memory function and memory decline

by Clinical Neuropsychologist Online | Tuesday, April 23, 2024 | Dementia

Alzheimer’s &Dementia, EarlyView. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: Md Shafiqur Rahman | April 23, 2024 Wiley: Alzheimer’s...

Linking white matter hyperintensities to regional cortical thinning, amyloid deposition, and synaptic density loss in Alzheimer’s disease

by Clinical Neuropsychologist Online | Tuesday, April 23, 2024 | Dementia

Abstract INTRODUCTION We investigated the association between white matter hyperintensities (WMH) and regional cortical thickness, amyloid and tau deposition, and synaptic density in the WMH-connected cortex using multimodal images. METHODS We included 107...

Alzheimer’s disease genetic risk score and neuroimaging in the FINGER lifestyle trial

by Clinical Neuropsychologist Online | Monday, April 22, 2024 | Dementia

Abstract INTRODUCTION We assessed a genetic risk score for Alzheimer’s disease (AD-GRS) and apolipoprotein E (APOE4) in an exploratory neuroimaging substudy of the FINGER trial. METHODS 1260 at-risk older individuals without dementia were randomized to...

Implementing global positioning system trackers for people with dementia who are at risk of wandering

by Clinical Neuropsychologist Online | Monday, April 22, 2024 | Dementia

Dementia, Volume 23, Issue 6, Page 964-980, August 2024. ObjectiveThe main aim of this study was to evaluate the feasibility and acceptability of using a GPS tracker to mitigate the risks associated with wandering for people with dementia and those caring for them and...

Japan‐Multimodal Intervention Trial for the Prevention of Dementia: A randomized controlled trial

by Clinical Neuropsychologist Online | Monday, April 22, 2024 | Dementia

Abstract INTRODUCTION We examined the efficacy of a multidomain intervention in preventing cognitive decline among Japanese older adults with mild cognitive impairment (MCI). METHODS Participants aged 65-85 years with MCI were randomized into intervention (management...
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