by Clinical Neuropsychologist | Friday, August 23, 2024 | Dementia
Abstract INTRODUCTION We aimed to assess the impact of cholinesterase inhibitors (ChEIs) and memantine on cognition, major adverse cardiovascular events (MACE) and mortality in dementia with Lewy bodies (DLB). METHODS A total of 1,095 incident DLB patients from the...
by Clinical Neuropsychologist | Friday, August 23, 2024 | Dementia
Abstract INTRODUCTION The paramagnetic iron, diamagnetic amyloid beta (Aβ) plaques and their interaction are crucial in Alzheimer’s disease (AD) pathogenesis, complicating non-invasive magnetic resonance imaging for prodromal AD detection. METHODS We used a...
by Clinical Neuropsychologist | Friday, August 23, 2024 | Dementia
Abstract INTRODUCTION We used clinical assessment records to provide pan-Canadian estimates of the prevalence and risks associated with recent (within the last 3 days) critical wandering among home care clients, with and without dementia. METHODS The data source is...
by Clinical Neuropsychologist | Thursday, August 22, 2024 | Dementia
Abstract INTRODUCTION We examined the associations of polygenic risk score (PRS) with Alzheimer’s disease (AD) and plasma biomarkers in the Chinese population. METHODS This population-based study used baseline data from MIND-China (2018; n = 4873) and follow-up...
by Clinical Neuropsychologist | Thursday, August 22, 2024 | Dementia
Abstract INTRODUCTION Reduced brain energy metabolism, mammalian target of rapamycin (mTOR) dysregulation, and extracellular amyloid beta (Aβ) oligomer (xcAβO) buildup are some well-known Alzheimer’s disease (AD) features; how they promote neurodegeneration is...
