Baseline cerebrospinal fluid complement balance is associated with longitudinal memory decline in relation to plasma p‑tau181 levels in mild cognitive impairment

by | Monday, September 21, 2026 | Dementia

Abstract INTRODUCTION The role of complement in Alzheimer’s disease (AD) remains unclear, particularly regarding tau pathology and memory decline. METHODS In 123 mild cognitive impairment (MCI) participants from Alzheimer’s Disease Neuroimaging Initiative...

Divergent associations of estimated cardiorespiratory fitness with cognitive trajectories in Chinese and U.S. middle‐aged and older adults: A descriptive cross‐national comparison from CHARLS and HRS

by | Thursday, September 17, 2026 | Dementia

Abstract INTRODUCTION The association between cardiorespiratory fitness (CRF) and cognition may differ across populations, but cross-cultural evidence remains limited. We explored whether estimated CRF (eCRF) shows divergent associations with cognitive trajectories in...

“Someone’s Acknowledged My Mum…in that Moment she Connected”: A Qualitative Study of Family Benefits of Elder Clowning for Persons With Dementia in Long-Term Care

by | Thursday, September 17, 2026 | Dementia

Dementia, Ahead of Print. Elder clowning is a multi-component, person-centred intervention delivered to persons living with dementia in long-term care to enhance quality of life through individualised social engagement. Although persons with dementia are the target...