by Clinical Neuropsychologist Online | Tuesday, June 4, 2024 | Dementia
Abstract INTRODUCTION Cognitive reserve might mitigate the risk of Alzheimer’s dementia among memory clinic patients. No study has examined the potential modifying role of stress on this relation. METHODS We examined cross-sectional associations of the cognitive...
by Clinical Neuropsychologist Online | Tuesday, June 4, 2024 | Dementia
Abstract INTRODUCTION The association of testosterone and cognitive decline is inconclusive, and its joint effect with neurofilaments light chain (NfL) remains largely unknown. METHODS A total of 581 non-demented older men in the Shanghai Aging Study were included....
by Clinical Neuropsychologist Online | Monday, June 3, 2024 | Dementia
Abstract INTRODUCTION Altered immune signatures are emerging as a central theme in neurodegenerative disease, yet little is known about immune responses in early-onset Alzheimer’s disease (EOAD). METHODS We examined single-cell RNA-sequencing (scRNA-seq) data...
by Clinical Neuropsychologist Online | Monday, June 3, 2024 | Dementia
Abstract INTRODUCTION Individuals referred to as Non-Demented with Alzheimer’s Neuropathology (NDAN) exhibit cognitive resilience despite presenting Alzheimer’s disease (AD) histopathological signs. Investigating the mechanisms behind this resilience may...
by Clinical Neuropsychologist Online | Monday, June 3, 2024 | Dementia
Abstract INTRODUCTION Recent growth in the functionality and use of technology has prompted an increased interest in the potential for remote or decentralized clinical trials in dementia. There are many potential benefits associated with decentralized medication...
