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Delineating cognitive resilience using fractal regulation: Cross‐sectional and longitudinal evidence from the Rush Memory and Aging Project

by Clinical Neuropsychologist Online | Monday, March 18, 2024 | Dementia

Abstract INTRODUCTION Degradation of fractal patterns in actigraphy independently predicts dementia risk. Such observations motivated the study to understand the role of fractal regulation in the context of neuropathologies. METHODS We examined associations of fractal...

Deriving life‐course residential histories in brain bank cohorts: A feasibility study

by Clinical Neuropsychologist Online | Monday, March 18, 2024 | Dementia

Abstract INTRODUCTION The exposome is theorized to interact with biological mechanisms to influence risk for Alzheimer’s disease but is not well-integrated into existing Alzheimer’s Disease Research Center (ADRC) brain bank data collection. METHODS We...

Wrist‐worn actigraphy in agitated late‐stage dementia patients: A feasibility study on digital inclusion

by Clinical Neuropsychologist Online | Monday, March 18, 2024 | Dementia

Abstract BACKGROUND Wrist-worn actigraphy can be an objective tool to assess sleep and other behavioral and psychological symptoms in dementia (BPSD). We investigated the feasibility of using wearable actigraphy in agitated late-stage dementia patients. METHODS...

Dementia and mild cognitive impairment screening in an emergency homeless shelter

by Clinical Neuropsychologist Online | Monday, March 18, 2024 | Dementia

Abstract INTRODUCTION Older adults represent the fastest growing segment of the homeless community. Little is known about the prevalence of dementia and mild cognitive impairment (MCI) in this population. METHODS Dementia and MCI screening using the Montreal Cognitive...

Association between hippocampal microglia, AD and LATE‐NC, and cognitive decline in older adults

by Clinical Neuropsychologist Online | Monday, March 18, 2024 | Dementia

Abstract INTRODUCTION This study investigates the relationship between microglia inflammation in the hippocampus, brain pathologies, and cognitive decline. METHODS Participants underwent annual clinical evaluations and agreed to brain donation. Neuropathologic...
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