by Clinical Neuropsychologist Online | Wednesday, March 20, 2024 | Dementia
Abstract BACKGROUND Variants in ABCA7, a member of the ABC transporter superfamily, have been associated with increased risk for developing late onset Alzheimer’s disease (LOAD). METHODS CRISPR-Cas9 was used to generate an Abca7V1613M variant in mice, modeling...
by Clinical Neuropsychologist Online | Wednesday, March 20, 2024 | Dementia
Abstract INTRODUCTION The Dementias Platform UK (DPUK) Data Portal is a data repository bringing together a wide range of cohorts. Neurodegenerative dementias are a group of diseases with highly heterogeneous pathology and an overlapping genetic component that is...
by Clinical Neuropsychologist Online | Wednesday, March 20, 2024 | Dementia
Abstract INTRODUCTION The Dementias Platform UK (DPUK) Data Portal is a data repository bringing together a wide range of cohorts. Neurodegenerative dementias are a group of diseases with highly heterogeneous pathology and an overlapping genetic component that is...
by Clinical Neuropsychologist Online | Wednesday, March 20, 2024 | Dementia
Abstract INTRODUCTION People with Down syndrome (DS) have high risk of developing Alzheimer’s disease (AD). This study examined mean ages of AD diagnosis and associations with co-occurring conditions among adults with DS from five European countries. METHODS...
by Clinical Neuropsychologist Online | Wednesday, March 20, 2024 | Dementia
Abstract INTRODUCTION Distance to physicians may explain some of the disparities in Alzheimer’s disease and related dementia (AD/ADRD) outcomes. METHODS We generated round trip distance between residences of decedents with AD/ADRD and the nearest neurologist and...
