by Clinical Neuropsychologist Online | Sunday, March 10, 2024 | Dementia
Abstract INTRODUCTION Hypertension and diabetes are modifiable risk factors for dementia. We aimed to assess rural-urban disparities in the diagnosis and treatment of these conditions among aging Indians. METHODS Participants (n = 6316) were from two parallel,...
by Clinical Neuropsychologist Online | Sunday, March 10, 2024 | Dementia
Abstract INTRODUCTION Although dementia-related proteinopathy has a strong negative impact on public health, and is highly heritable, understanding of the related genetic architecture is incomplete. METHODS We applied multidimensional generalized partial credit...
by Clinical Neuropsychologist Online | Saturday, March 9, 2024 | Dementia
Abstract INTRODUCTION The BIN1 coding variant rs138047593 (K358R) is linked to Late-Onset Alzheimer’s Disease (LOAD) via targeted exome sequencing. METHODS To elucidate the functional consequences of this rare coding variant on brain amyloidosis and...
by Clinical Neuropsychologist Online | Saturday, March 9, 2024 | Dementia
Abstract Dementia research lacks appropriate representation of diverse groups who often face substantial adversity and greater risk of dementia. Current research participants are primarily well-resourced, non-Hispanic White, cisgender adults who live close to academic...
by Clinical Neuropsychologist Online | Friday, March 8, 2024 | Dementia
Abstract INTRODUCTION Federal policies and guidelines have expanded the return of individual results to participants and expectations for data sharing between investigators and through repositories. Here, we report investigators’ and study participants’ views and...