by Clinical Neuropsychologist Online | Tuesday, April 30, 2024 | Dementia
Abstract INTRODUCTION Previous approaches pursuing in vivo staging of tau pathology in Alzheimer’s disease (AD) have typically relied on neuropathologically defined criteria. In using predefined systems, these studies may miss spatial deposition patterns which...
by Clinical Neuropsychologist Online | Sunday, April 28, 2024 | Dementia
Abstract INTRODUCTION Increasing evidence suggests that metabolic impairments contribute to early Alzheimer’s disease (AD) mechanisms and subsequent dementia. Signals in metabolic pathways conserved across species can facilitate translation. METHODS We...
by Clinical Neuropsychologist Online | Saturday, April 27, 2024 | Dementia
Alzheimer’s &Dementia, EarlyView. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: Pasquale Gallina, Francesco Lolli, Berardino Porfirio | April...
by Clinical Neuropsychologist Online | Saturday, April 27, 2024 | Dementia
Abstract INTRODUCTION Animal research has shown that tau pathology in the locus coeruleus (LC) is associated with reduced norepinephrine signaling, lower projection density to the medial temporal lobe (MTL), atrophy, and cognitive impairment. We investigated the...
by Clinical Neuropsychologist Online | Saturday, April 27, 2024 | Dementia
Abstract INTRODUCTION This study delineated the interrelationships between subclinical alterations in the left heart, cerebrospinal fluid (CSF), Alzheimer’s disease (AD) biomarkers, and cognition. METHODS Multiple linear regressions were conducted in 1244...
