by Clinical Neuropsychologist Online | Tuesday, February 27, 2024 | Dementia
Abstract INTRODUCTION Alzheimer’s disease (AD) involves the complement cascade, with complement component 3 (C3) playing a key role. However, the relationship between C3 and amyloid beta (Aβ) in blood is limited. METHODS Plasma C3 and Aβ oligomerization tendency...
by Clinical Neuropsychologist Online | Monday, February 26, 2024 | Dementia
Dementia, Volume 23, Issue 4, Page 584-609, May 2024. Participating in physical activity is beneficial for older people with dementia. Little is known however about the perceptions of people living with dementia undertaking an online-delivered exercise program. This...
by Clinical Neuropsychologist Online | Saturday, February 24, 2024 | Dementia
Abstract The fifth annual workshop on Principles and Techniques for Improving Preclinical Translation of Alzheimer’s Disease Research was held in May 2023 at The Jackson Laboratory in Bar Harbor, Maine, USA. The workshop was established in 2018 to address...
by Clinical Neuropsychologist Online | Saturday, February 24, 2024 | Dementia
Abstract INTRODUCTION Increasing evidence suggests that amyloid reduction could serve as a plausible surrogate endpoint for clinical and cognitive efficacy. The double-blind phase 3 DIAN-TU-001 trial tested clinical and cognitive declines with increasing doses of...
by Clinical Neuropsychologist Online | Saturday, February 24, 2024 | Dementia
Abstract INTRODUCTION Individuals in socioeconomically disadvantaged neighborhoods exhibit increased risk for impaired cognitive function. Whether this association relates to the major dementia-related neuropathologies is unknown. METHODS This cross-sectional study...
