by Clinical Neuropsychologist Online | Thursday, February 29, 2024 | Dementia
Abstract INTRODUCTION Entorhinal cortex (EC) is the first cortical region to exhibit neurodegeneration in Alzheimer’s disease (AD), associated with EC grid cell dysfunction. Given the role of grid cells in path integration (PI)–based spatial behaviors, we...
by Clinical Neuropsychologist Online | Wednesday, February 28, 2024 | Dementia
Abstract INTRODUCTION Alzheimer’s disease (AD) trial participants are often screened for eligibility by brain amyloid positron emission tomography/cerebrospinal fluid (PET/CSF), which is inefficient as many are not amyloid positive. Use of blood-based biomarkers...
by Clinical Neuropsychologist Online | Tuesday, February 27, 2024 | Dementia
Abstract INTRODUCTION Alzheimer’s disease (AD) involves the complement cascade, with complement component 3 (C3) playing a key role. However, the relationship between C3 and amyloid beta (Aβ) in blood is limited. METHODS Plasma C3 and Aβ oligomerization tendency...
by Clinical Neuropsychologist Online | Monday, February 26, 2024 | Dementia
Dementia, Volume 23, Issue 4, Page 584-609, May 2024. Participating in physical activity is beneficial for older people with dementia. Little is known however about the perceptions of people living with dementia undertaking an online-delivered exercise program. This...
by Clinical Neuropsychologist Online | Saturday, February 24, 2024 | Dementia
Abstract The fifth annual workshop on Principles and Techniques for Improving Preclinical Translation of Alzheimer’s Disease Research was held in May 2023 at The Jackson Laboratory in Bar Harbor, Maine, USA. The workshop was established in 2018 to address...