by Clinical Neuropsychologist Online | Saturday, February 24, 2024 | Dementia
Abstract INTRODUCTION Increasing evidence suggests that amyloid reduction could serve as a plausible surrogate endpoint for clinical and cognitive efficacy. The double-blind phase 3 DIAN-TU-001 trial tested clinical and cognitive declines with increasing doses of...
by Clinical Neuropsychologist Online | Saturday, February 24, 2024 | Dementia
Abstract INTRODUCTION Individuals in socioeconomically disadvantaged neighborhoods exhibit increased risk for impaired cognitive function. Whether this association relates to the major dementia-related neuropathologies is unknown. METHODS This cross-sectional study...
by Clinical Neuropsychologist Online | Saturday, February 24, 2024 | Dementia
Abstract INTRODUCTION Little is known regarding quality of life (QoL) in dementia with Lewy bodies (DLB), particularly in advanced stages. METHODS Dyads of individuals with moderate–advanced DLB and their primary caregivers were recruited from specialty clinics,...
by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Dementia
Abstract INTRODUCTION We investigated whether retinal capillary perfusion is a biomarker of cerebral small vessel disease and impaired cognition among Black Americans, an understudied group at higher risk for dementia. METHODS We enrolled 96 Black Americans without...
by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Dementia
Abstract INTRODUCTION Evidence is limited on the role of mid-life Dietary Approaches to Stop Hypertension (DASH) diet in late-life subjective cognitive complaints (SCCs). METHODS We included 5116 women (mean age in 1985–1991: 46 years) from the New York University...
