by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Dementia
Abstract INTRODUCTION Many lifestyle factors have been associated with dementia, but there is limited evidence of how these group together. The aim of this study was to examine the clustering of lifestyle behaviors and associations with dementia. METHODS This...
by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Dementia
Abstract INTRODUCTION There remains an urgent need to identify preclinical pathophysiological mechanisms of Alzheimer’s disease (AD) development in high-risk, racially diverse populations. We explored the relationship between cerebrospinal fluid (CSF) markers of...
by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Dementia
Abstract INTRODUCTION We discovered that the APOE3 Christchurch (APOE3Ch) variant may provide resistance to Alzheimer’s disease (AD). This resistance may be due to reduced pathological interactions between ApoE3Ch and heparan sulfate proteoglycans (HSPGs)....
by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Dementia
Abstract INTRODUCTION The U.S. study to protect brain health through lifestyle intervention to reduce risk (U.S. POINTER) is conducted to confirm and expand the results of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)...
by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Dementia
Abstract INTRODUCTION Verbal fluency tasks are common in Alzheimer’s disease (AD) assessments. Yet, standard valid response counts fail to reveal disease-specific semantic memory patterns. Here, we leveraged automated word-property analysis to capture...
