by Clinical Neuropsychologist | Tuesday, July 30, 2024 | Dementia
Abstract INTRODUCTION Plasma has been proposed as an alternative to cerebrospinal fluid (CSF) for measuring Alzheimer’s disease (AD) biomarkers, but no studies have analyzed in detail which biofluid is more informative for genetics studies of AD. METHOD Eleven...
by Clinical Neuropsychologist | Monday, July 29, 2024 | Dementia
Abstract INTRODUCTION Housing insecurity is rising among older adults; health researchers know little about how this may impact their cognitive health. We investigated links between foreclosure and older adults’ memory and probability of dementia. METHODS Using the...
by Clinical Neuropsychologist | Monday, July 29, 2024 | Dementia
Abstract INTRODUCTION Recent clinical trials of amyloid beta (Aβ)-targeting therapies in Alzheimer’s disease (AD) have demonstrated a clinical benefit over 18 months, but their long-term impact on disease trajectory is not yet understood. We propose a framework...
by Clinical Neuropsychologist | Monday, July 29, 2024 | Dementia
Abstract INTRODUCTION Unraveling how Alzheimer’s disease (AD) genetic risk is related to neuropathological heterogeneity, and whether this occurs through specific biological pathways, is a key step toward precision medicine. METHODS We computed pathway-specific...
by Clinical Neuropsychologist | Monday, July 29, 2024 | Dementia
Abstract INTRODUCTION COVID-19 had devastating impacts worldwide. However, most research examining the impact of dementia on COVID-19 outcomes has been conducted in Europe and Asia and has not examined dementia subtypes. METHODS A retrospective analysis of electronic...