by Clinical Neuropsychologist Online | Sunday, August 30, 2026 | Dementia
Abstract INTRODUCTION Developmental neurotoxicant exposures (e.g., lead [Pb]) are suspected contributors to dementia. Dementia is characterized by amyloid beta (Aβ) plaques and dysregulated metabolism. To better understand the relationship between environment and...
by Clinical Neuropsychologist Online | Thursday, August 27, 2026 | Dementia
Dementia, Ahead of Print. Caring for a parent with dementia constitutes a profound relational and existential transition for adult children, extending beyond functional caregiving demands to processes of identity negotiation and reconstruction. Although extensive...
by Clinical Neuropsychologist Online | Thursday, August 27, 2026 | Dementia
Dementia, Ahead of Print. Health-related quality of life reflects individuals’ perceptions of how a health condition affects their physical, psychological, and social functioning. Amid increasing pressures on primary care systems, people living with dementia are...
by Clinical Neuropsychologist Online | Wednesday, August 26, 2026 | Dementia
Abstract INTRODUCTION Functional brain network alterations associated with Alzheimer’s disease (AD) pathology, including amyloid beta (Aβ) and phosphorylated tau (p-tau), are difficult to interpret due to overlapping aging-associated and non-amyloid biological...
by Clinical Neuropsychologist Online | Wednesday, August 26, 2026 | Dementia
Abstract In clinical studies, it is scientifically important, and a regulatory expectation, that objectives be translated into key clinical questions by specifically defining treatment effects to be estimated. Estimands are part of a structured framework, as presented...
