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The role of polygenic risk in Alzheimer’s disease prediction for African Americans

by Clinical Neuropsychologist Online | Wednesday, August 5, 2026 | Dementia

Abstract INTRODUCTION African Americans (AAs) face a higher risk of Alzheimer’s disease and related dementias (ADRD) than European Americans (EUs), yet the utility of polygenic risk scores (PRS) in AAs remains underexplored. METHODS A standardized dementia PRS...

Lower cardiac output is a risk factor for faster cerebral atrophy over a 11‐year follow‐up period in APOE‐ε4 carriers

by Clinical Neuropsychologist Online | Tuesday, August 4, 2026 | Dementia

Abstract INTRODUCTION Subclinical lower cardiac output (volume of blood pumped per minute) cross-sectionally relates to smaller cerebral gray matter volumes in older adults. This study relates cardiac output to longitudinal gray matter volumes among middle-aged and...

Visit‐to‐visit systolic blood pressure variability, blood pressure treatment intensity, and cognitive decline

by Clinical Neuropsychologist Online | Friday, July 31, 2026 | Dementia

Abstract INTRODUCTION Visit-to-visit blood pressure variability (BPV) may be associated with cognitive decline beyond mean blood pressure (BP), but its relevance across treatment contexts remains uncertain. METHODS We pooled individual-participant data from Action to...

From mapping evidence to engaging voices: Paving the way for research on the social determinants of dementia

by Clinical Neuropsychologist Online | Friday, July 31, 2026 | Dementia

Alzheimer’s &Dementia, Volume 22, Issue 8, August 2026. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: | July 31, 2026 Neuro-Dementia Previous...

The role of vascular risk factors in white matter tract microstructure: a multi‐cohort study in older adults

by Clinical Neuropsychologist Online | Friday, July 31, 2026 | Dementia

Abstract INTRODUCTION Vascular risk factors (VRFs) contribute to white matter microstructural degeneration, but their tract-specific contributions are unclear. We assessed the independent associations of four major VRFs with white matter microstructure in a large,...
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