by Clinical Neuropsychologist | Wednesday, January 8, 2025 | Dementia
Abstract Aging rhesus macaques provide a unique model for learning how age and inflammation drive early-stage pathology in sporadic Alzheimer’s disease, and for testing potential therapeutics. Unlike mice, aging macaques have extensive association cortices and...
by Clinical Neuropsychologist | Tuesday, January 7, 2025 | Dementia
Abstract INTRODUCTION Cerebrovascular pathologic changes (CVPC) are prevalent and associated with dementia in those ≥ 90 years. However, CVPC associations to traditional risk factors (hypertension, diabetes, and hyperlipidemia) are variable. We hypothesized that...
by Clinical Neuropsychologist | Monday, January 6, 2025 | Dementia
Alzheimer’s &Dementia, EarlyView. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: Ozioma C. Okonkwo, Monica Rivera‐Mindt, Michael W. Weiner, for...
by Clinical Neuropsychologist | Friday, January 3, 2025 | Dementia
Abstract Background The brain is shielded from the peripheral circulation by central nervous system (CNS) barriers, comprising the well-known blood-brain barrier (BBB) and the less recognized blood-cerebrospinal fluid (CSF) barrier located within the brain ventricles....
by Clinical Neuropsychologist | Friday, January 3, 2025 | Dementia
Abstract Background Alzheimer’s disease (AD) is a complex neurodegenerative disorder characterized by hallmark pathologies that affect many brain regions, including the cellular microenvironment with the hippocampus, ultimately leading to profound deficits in...
