by Clinical Neuropsychologist | Wednesday, May 8, 2024 | Dementia
Abstract INTRODUCTION Cerebrovascular dysfunction is a pathological hallmark of Alzheimer’s disease (AD). Nevertheless, detecting cerebrovascular changes within bulk tissues has limited our ability to characterize proteomic alterations from less abundant cell...
by Clinical Neuropsychologist | Wednesday, May 8, 2024 | Dementia
Abstract BACKGROUND Alzheimer’s disease (AD) is the most common cause of dementia worldwide, with apolipoprotein Eε4 (APOEε4) being the strongest genetic risk factor. Current clinical diagnostic imaging focuses on amyloid and tau; however, new methods are needed...
by Clinical Neuropsychologist | Wednesday, May 8, 2024 | Dementia
Abstract INTRODUCTION Platelets serve as the primary peripheral reservoir of amyloid beta (Aβ). However, there is limited research on platelet markers in routine blood examinations, particularly with regard to the large platelet ratio (P-LCR) in Alzheimer’s...
by Clinical Neuropsychologist | Tuesday, May 7, 2024 | Dementia
Dementia, Volume 23, Issue 5, Page 757-778, July 2024. Hope is an important but overlooked phenomenon in dementia studies. Few studies have examined how people with dementia experience or perceive hope, possibly because it is seen as a diagnosis without hope. In this...
by Clinical Neuropsychologist | Monday, May 6, 2024 | Dementia
Abstract We investigate Alzheimer’s disease and related dementia (ADRD) prevalence, incidence rate, and risk factors in individuals racialized as Asian and/or Asian-American and assess sample representation. Prevalence, incidence rate, risk factors, and...
