by Clinical Neuropsychologist Online | Tuesday, October 20, 2026 | Dementia
ABSTRACT INTRODUCTION Diabetes is a major risk factor for Alzheimer’s disease (AD), and both diseases involve mitochondrial dysfunction. Changes in mitochondrial DNA (mtDNA) can influence energy metabolism, cellular signaling, and epigenetic programming, thereby...
by Clinical Neuropsychologist Online | Monday, October 19, 2026 | Dementia
Abstract State dementia strategic plans provide policy and practice recommendations to reduce the risk, progression, and impact of dementia. Yet there is little systematic understanding of the contents of state plans nor how they aim to influence dementia strategy....
by Clinical Neuropsychologist Online | Saturday, October 17, 2026 | Dementia
Abstract INTRODUCTION Machine learning algorithms applied to neuroimaging may aid diagnosis and disease monitoring. This study aimed to derive neuroimaging signatures of brain aging (Spatial Pattern of Atrophy for Recognition–Brain Age [SPARE-BA]) and...
by Clinical Neuropsychologist Online | Friday, October 16, 2026 | Dementia
Abstract The neuromodulatory subcortical system (NSS) includes thermoregulatory neurons that maintain core body temperature (Tb) and brain temperature within a narrow, diurnally varying range. Cellular pathways in NSS neurons implicated in Alzheimer’s disease...
by Clinical Neuropsychologist Online | Thursday, October 15, 2026 | Dementia
Abstract INTRODUCTION Preliminary evidence suggests a link between attention-deficit/hyperactivity disorder (ADHD) and later-life cognitive impairment. Whether genetic risk for ADHD, estimated using an ADHD polygenic risk score (ADHD-PRS), is associated with incident...