by Clinical Neuropsychologist Online | Friday, July 10, 2026 | Dementia
Abstract Gene-based therapies show increasing promise for the treatment of neurologic disease. In 2016, nusinersen, an RNA-based therapy, was approved for children with spinal muscular atrophy (SMA). Over 200 clinical trials have utilized gene therapy approaches for a...
by Clinical Neuropsychologist Online | Friday, July 10, 2026 | Dementia
Abstract INTRODUCTION We explored how people with dementia (PwD) and their carers navigate Peru’s health system for diagnosis and treatment. METHODS We interviewed PwD (n = 4), carers (n = 18), and healthcare workers (n = 17) from four sites. We developed a...
by Clinical Neuropsychologist Online | Friday, July 10, 2026 | Dementia
Abstract INTRODUCTION The Apolipoprotein E ε4 allele (APOE-ε4) is a well-established dementia risk factor among non-Latino White individuals but remains understudied among Asian Americans. We estimated its association with dementia risk among Chinese, Japanese,...
by Clinical Neuropsychologist Online | Friday, July 10, 2026 | Dementia
Abstract INTRODUCTION Perioperative neurocognitive disorder is a common and debilitating complication in the elderly, yet its cellular and molecular mechanisms in the aging brain remain poorly understood. METHODS Using aged mice, we examined the impact of abdominal...
by Clinical Neuropsychologist Online | Thursday, July 9, 2026 | Dementia
Dementia, Ahead of Print. Family caregivers of persons with dementia often face chronic stress, disrupted sleep, and emotional exhaustion. While adult day programs provide daytime respite, support during nighttime, when caregiving responsibilities can intensify,...
