by Clinical Neuropsychologist | Tuesday, November 19, 2024 | Dementia
Abstract BACKGROUND Approximately 40% of people aged ≥ 65 experience memory loss, particularly in episodic memory. Identifying the genetic basis of episodic memory decline is crucial for uncovering its underlying causes. METHODS We investigated common and rare genetic...
by Clinical Neuropsychologist | Tuesday, November 19, 2024 | Dementia
Abstract INTRODUCTION A key goal of the Alzheimer’s Disease NeuroImaging Initiative (ADNI) positron emission tomography (PET) Core is to harmonize quantification of β-amyloid (Aβ) and tau PET image data across multiple scanners and tracers. METHODS We developed...
by Clinical Neuropsychologist | Tuesday, November 19, 2024 | Dementia
Abstract BACKGROUND The history from a relative or caregiver is an important tool for differentiating neurodegenerative disease. We characterized patterns of caregiver questionnaire responses, at diagnosis and follow-up, on the Cambridge Behavioural Inventory (CBI)....
by Clinical Neuropsychologist | Tuesday, November 19, 2024 | Dementia
Abstract INTRODUCTION Elevated plasma homocysteine (Hcy) is associated with an increased risk of developing neurodegenerative diseases; however, its relationship with the apolipoprotein E (APOE) ε4 allele has not been well characterized. METHODS Participants...
by Clinical Neuropsychologist | Tuesday, November 19, 2024 | Dementia
Dementia, Volume 24, Issue 2, Page 249-268, February 2025. Background and ObjectivesCulturally diverse informal caregivers of community-dwelling persons with dementia face challenges in accessing dementia care resources due to language barriers and cultural stigmas...