by Clinical Neuropsychologist | Tuesday, April 30, 2024 | Dementia
Abstract Experimental laboratory research has an important role to play in dementia prevention. Mechanisms underlying modifiable risk factors for dementia are promising targets for dementia prevention but are difficult to investigate in human populations due to...
by Clinical Neuropsychologist | Tuesday, April 30, 2024 | Dementia
Abstract INTRODUCTION Previous approaches pursuing in vivo staging of tau pathology in Alzheimer’s disease (AD) have typically relied on neuropathologically defined criteria. In using predefined systems, these studies may miss spatial deposition patterns which...
by Clinical Neuropsychologist | Sunday, April 28, 2024 | Dementia
Abstract INTRODUCTION Increasing evidence suggests that metabolic impairments contribute to early Alzheimer’s disease (AD) mechanisms and subsequent dementia. Signals in metabolic pathways conserved across species can facilitate translation. METHODS We...
by Clinical Neuropsychologist | Saturday, April 27, 2024 | Dementia
Alzheimer’s &Dementia, EarlyView. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: Pasquale Gallina, Francesco Lolli, Berardino Porfirio | April...
by Clinical Neuropsychologist | Saturday, April 27, 2024 | Dementia
Abstract INTRODUCTION Animal research has shown that tau pathology in the locus coeruleus (LC) is associated with reduced norepinephrine signaling, lower projection density to the medial temporal lobe (MTL), atrophy, and cognitive impairment. We investigated the...