by Clinical Neuropsychologist | Wednesday, August 28, 2024 | Dementia
Abstract INTRODUCTION Normal pressure hydrocephalus (NPH) patients undergoing cortical shunting frequently show early Alzheimer’s disease (AD) pathology on cortical biopsy, which is predictive of progression to clinical AD. The objective of this study was to use...
by Clinical Neuropsychologist | Monday, August 26, 2024 | Dementia
Dementia, Volume 24, Issue 1, Page 3-13, January 2025. Stigma surrounding dementia is a significant issue affecting individuals and communities leading to discrimination towards those living with the condition. However, the changing paradigm in dementia support to...
by Clinical Neuropsychologist | Friday, August 23, 2024 | Dementia
Abstract INTRODUCTION The in vivo detection of mixed Alzheimer’s disease (AD) and α-synuclein (αSyn) pathology is important for clinical management and prognostic stratification. We investigated the contribution of αSyn pathology, detected by cerebrospinal fluid...
by Clinical Neuropsychologist | Friday, August 23, 2024 | Dementia
Abstract INTRODUCTION We aimed to assess the impact of cholinesterase inhibitors (ChEIs) and memantine on cognition, major adverse cardiovascular events (MACE) and mortality in dementia with Lewy bodies (DLB). METHODS A total of 1,095 incident DLB patients from the...
by Clinical Neuropsychologist | Friday, August 23, 2024 | Dementia
Abstract INTRODUCTION The paramagnetic iron, diamagnetic amyloid beta (Aβ) plaques and their interaction are crucial in Alzheimer’s disease (AD) pathogenesis, complicating non-invasive magnetic resonance imaging for prodromal AD detection. METHODS We used a...
