by Clinical Neuropsychologist Online | Monday, September 2, 2024 | Dementia
Abstract INTRODUCTION The relationship between cerebrovascular disease (CVD) and amyloid beta (Aβ) in Alzheimer’s disease (AD) is understudied. We hypothesized that magnetic resonance imaging (MRI)–based CVD biomarkers—including cerebral microbleeds (CMBs),...
by Clinical Neuropsychologist Online | Monday, September 2, 2024 | Dementia
Abstract INTRODUCTION We evaluated preliminary feasibility of a digital, culturally-informed approach to recruit and screen participants for the Alzheimer’s Disease Neuroimaging Initiative (ADNI4). METHODS Participants were recruited using digital advertising...
by Clinical Neuropsychologist Online | Monday, September 2, 2024 | Dementia
Abstract INTRODUCTION Brain network dynamics have been extensively explored in patients with amnestic mild cognitive impairment (aMCI); however, differences in single- and multiple-domain aMCI (SD-aMCI and MD-aMCI) remain unclear. METHODS Using multicenter datasets,...
by Clinical Neuropsychologist Online | Saturday, August 31, 2024 | Dementia
Abstract INTRODUCTION CD33 rs3865444 and hypertension (HTN) are related to cognitive impairment, individually. However, little is known about their combined effects on cognitive function in older adults. METHODS This population-based study included 4368 dementia-free...
by Clinical Neuropsychologist Online | Saturday, August 31, 2024 | Dementia
Abstract INTRODUCTION Multi-omics studies in Alzheimer’s disease (AD) revealed many potential disease pathways and therapeutic targets. Despite their promise of precision medicine, these studies lacked Black Americans (BA) and Latin Americans (LA), who are...
