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Blood‐based multivariate methylation risk score for cognitive impairment and dementia

by Clinical Neuropsychologist Online | Wednesday, August 28, 2024 | Dementia

Abstract INTRODUCTION The established link between DNA methylation and pathophysiology of dementia, along with its potential role as a molecular mediator of lifestyle and environmental influences, positions blood-derived DNA methylation as a promising tool for early...

How fiber bundle alterations differ in presumed LATE and amnestic Alzheimer’s disease

by Clinical Neuropsychologist Online | Wednesday, August 28, 2024 | Dementia

Abstract INTRODUCTION Typical Alzheimer’s disease (AD) and limbic-predominant age-related TAR DNA-binding protein 43 (TDP-43) encephalopathy (LATE) are two neurodegenerative diseases that present with a similar initial amnestic clinical phenotype but are...

The moderating role of information processing speed in the relationship between brain remodeling and episodic memory in amnestic mild cognitive impairment

by Clinical Neuropsychologist Online | Wednesday, August 28, 2024 | Dementia

Abstract INTRODUCTION The role of information processing speed (IPS) on relationships between episodic memory (EM) and central remodeling features in amnestic mild cognitive impairment (aMCI) was investigated. METHODS Neuropsychological evaluations and multimodal...

Alzheimer’s disease and its family history reduce the risk of non‐Hodgkin’s lymphoma: A Mendelian randomization study

by Clinical Neuropsychologist Online | Wednesday, August 28, 2024 | Dementia

Alzheimer’s &Dementia, EarlyView. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: Zilong Wang, Binyang Song, Jinhua Wang, Xiaobo Wang, Bo Tang |...

Alzheimer’s disease CSF biomarkers correlate with early pathology and alterations in neuronal and glial gene expression

by Clinical Neuropsychologist Online | Wednesday, August 28, 2024 | Dementia

Abstract INTRODUCTION Normal pressure hydrocephalus (NPH) patients undergoing cortical shunting frequently show early Alzheimer’s disease (AD) pathology on cortical biopsy, which is predictive of progression to clinical AD. The objective of this study was to use...
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