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Addressing artifactual bias in large, automated MRI analyses of brain development

by Clinical Neuropsychologist | Tuesday, July 1, 2025 | Neuroscience

Nature Neuroscience, Published online: 01 July 2025; doi:10.1038/s41593-025-01990-7As large-scale neurodevelopmental MRI studies gain prominence, the authors identify tradeoffs between sample size and quality control that can dramatically affect results, and they...

Exploring Auditory Interconnectivity One Sound at a Time

by Clinical Neuropsychologist | Tuesday, July 1, 2025 | Neuroscience

As the summer lawn mowers roar outside my window, I cannot help but think about how that sound is being processed in my brain. Like many people, I think about the process as quite hierarchical – with the auditory nerve in my ear registering the sound and then...

Human CLOCK enhances neocortical function

by Clinical Neuropsychologist | Monday, June 30, 2025 | Neuroscience

Nature Neuroscience, Published online: 30 June 2025; doi:10.1038/s41593-025-01993-4Regulation of gene expression is a facet of human brain specialization. Here, the authors show that human-like expression of the CLOCK gene in the mouse neocortex enhances cognitive...

Fine-mapping genomic loci refines bipolar disorder risk genes

by Clinical Neuropsychologist | Wednesday, June 25, 2025 | Neuroscience

Nature Neuroscience, Published online: 25 June 2025; doi:10.1038/s41593-025-01998-zThis study used fine-mapping to analyze genetic regions associated with bipolar disorder, identifying specific risk genes and providing new insights into the biology of the condition...

Large-scale high-density brain-wide neural recording in nonhuman primates

by Clinical Neuropsychologist | Monday, June 23, 2025 | Neuroscience

Nature Neuroscience, Published online: 23 June 2025; doi:10.1038/s41593-025-01976-5Neuropixels 1.0 NHP is a 45-mm, high-density silicon probe capable of recording large numbers of neurons with single-neuron resolution from most areas in a macaque’s brain. If you do...
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