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Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing

by Clinical Neuropsychologist | Wednesday, September 17, 2025 | Neuroscience

Nature Neuroscience, Published online: 17 September 2025; doi:10.1038/s41593-025-02053-7The authors develop a new computational system for high-throughput mapping of synaptic connectivity using two-photon holographic optogenetics and intracellular recordings. If you...

High-throughput synaptic connectivity mapping using in vivo two-photon holographic optogenetics and compressive sensing

by Clinical Neuropsychologist | Wednesday, September 17, 2025 | Neuroscience

Nature Neuroscience, Published online: 17 September 2025; doi:10.1038/s41593-025-02024-yUsing two-photon optogenetics, electrical recordings and sparse signal reconstruction, the authors demonstrate in vivo synaptic connectivity mapping in the mouse visual cortex. If...

Author Correction: Spatial transcriptomics reveals the distinct organization of mouse prefrontal cortex and neuronal subtypes regulating chronic pain

by Clinical Neuropsychologist | Tuesday, September 16, 2025 | Neuroscience

Nature Neuroscience, Published online: 16 September 2025; doi:10.1038/s41593-025-02077-zAuthor Correction: Spatial transcriptomics reveals the distinct organization of mouse prefrontal cortex and neuronal subtypes regulating chronic pain If you do not see content...

Augmenting AMPA receptor signaling after spinal cord injury increases ependymal-derived neural stem/progenitor cell migration and promotes functional recovery

by Clinical Neuropsychologist | Monday, September 15, 2025 | Neuroscience

Nature Neuroscience, Published online: 15 September 2025; doi:10.1038/s41593-025-02044-8Hachem et al. show that AMPAR signaling drives the acute activation of ependymal-derived neural stem/progenitor cells after spinal cord injury and that this mechanism can be...

Recurrent pattern completion drives the neocortical representation of sensory inference

by Clinical Neuropsychologist | Monday, September 15, 2025 | Neuroscience

Nature Neuroscience, Published online: 15 September 2025; doi:10.1038/s41593-025-02055-5Neurons that respond emergently to illusory contours drive pattern completion in V1. Pattern completion in lower cortical areas may therefore mediate perceptual inference by...
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