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Intensive longitudinal brain imaging reveals personalized signatures of chronic pain

by Clinical Neuropsychologist | Thursday, March 5, 2026 | Neuroscience

Nature Neuroscience, Published online: 05 March 2026; doi:10.1038/s41593-026-02238-8Tracking ongoing spontaneous pain in individuals with chronic pain is challenging. Using intensive longitudinal functional magnetic resonance imaging (fMRI) combined with continuous...

From an Outsider to a Champion for the Cognitive Neuroscience of Emotion

by Clinical Neuropsychologist | Wednesday, March 4, 2026 | Neuroscience

Q&A with Joseph LeDoux When asked about his career journey in cognitive neuroscience. Joseph LeDoux points to a documentary about Beatles producer George Martin. In the film, Martin says something that has always resonated with LeDoux. When asked why he thinks he...

Natural behavior is what you do, not just where you are

by Clinical Neuropsychologist | Friday, February 27, 2026 | Neuroscience

Nature Neuroscience, Published online: 27 February 2026; doi:10.1038/s41593-026-02225-zAs neuroscience increasingly recognizes that understanding the brain requires studying natural behavior, it has begun to adopt more naturalistic experimental environments as a means...

Personalized brain decoding of spontaneous pain in individuals with chronic pain

by Clinical Neuropsychologist | Thursday, February 26, 2026 | Neuroscience

Nature Neuroscience, Published online: 26 February 2026; doi:10.1038/s41593-026-02221-3Lee et al. show that personalized brain-decoding models derived from intensive longitudinal fMRI data can track spontaneous pain in individuals with chronic pain, highlighting the...

Magnetic resonance microscopy maps widespread effects of Alzheimer’s disease on brain structures and behavior in mice

by Clinical Neuropsychologist | Thursday, February 26, 2026 | Neuroscience

Nature Neuroscience, Published online: 26 February 2026; doi:10.1038/s41593-025-02199-4Alzheimer’s disease alters brain structure broadly, but its regional impact is poorly mapped. Here, the authors show that App and Psen1 mutations in mice cause volume changes across...
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