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A sensory–motor theory of the neocortex

by Clinical Neuropsychologist | Thursday, June 27, 2024 | Neuroscience

Nature Neuroscience, Published online: 27 June 2024; doi:10.1038/s41593-024-01673-9Recent studies suggest a close interaction between sensory and motor processes across the neocortex. In this Perspective, Rao proposes active predictive coding as a sensory–motor theory...

Dissecting the epigenetic regulation of human brain organoid development in single cells

by Clinical Neuropsychologist | Tuesday, June 25, 2024 | Neuroscience

Nature Neuroscience, Published online: 25 June 2024; doi:10.1038/s41593-024-01653-zWe present a developmental atlas that offers insight into sequential epigenetic changes underlying early human brain development modeled in organoids, which reconstructs the...

Single-cell epigenomic reconstruction of developmental trajectories from pluripotency in human neural organoid systems

by Clinical Neuropsychologist | Monday, June 24, 2024 | Neuroscience

Nature Neuroscience, Published online: 24 June 2024; doi:10.1038/s41593-024-01652-0The mechanisms underlying human cell diversity are unclear. Here the authors provide a single-cell epigenome map of human neural organoid development and dissect how epigenetic changes...

A high-density 1,024-channel probe for brain-wide recordings in non-human primates

by Clinical Neuropsychologist | Monday, June 24, 2024 | Neuroscience

Nature Neuroscience, Published online: 24 June 2024; doi:10.1038/s41593-024-01692-6A probe incorporating 1,024 simultaneously recorded channels with shank length up to 90 mm exhibits high chronic recording stability and enables brain-wide large-scale neural population...

Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice

by Clinical Neuropsychologist | Friday, June 21, 2024 | Neuroscience

Nature Neuroscience, Published online: 21 June 2024; doi:10.1038/s41593-024-01684-6The features of astrocytes surrounding CNS lesions are unclear. Here the authors show that after spinal cord injury or stroke in mice, mature astrocytes dedifferentiate, proliferate and...
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