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Local origin of excitatory–inhibitory tuning equivalence in a cortical network

by Clinical Neuropsychologist Online | Friday, March 15, 2024 | Neuroscience

Nature Neuroscience, Published online: 15 March 2024; doi:10.1038/s41593-024-01588-5Cortical excitatory neurons are narrowly tuned to sensory inputs, but the tuning of interneurons is perceived as broad and irregular. Duszkiewicz et al. demonstrate that interneuron...

Liprin-α proteins are master regulators of human presynapse assembly

by Clinical Neuropsychologist Online | Tuesday, March 12, 2024 | Neuroscience

Nature Neuroscience, Published online: 12 March 2024; doi:10.1038/s41593-024-01592-9This paper identifies the evolutionarily conserved liprin-α protein family as key mediators of presynaptic assembly in human neurons. Their recruitment to sites formed by contacting...

In conversation with Igor Adameyko

by Clinical Neuropsychologist Online | Tuesday, March 12, 2024 | Neuroscience

Nature Neuroscience, Published online: 12 March 2024; doi:10.1038/s41593-024-01614-6As Nature Neuroscience celebrates its 25th anniversary, we are having conversations with both established leaders in the field and those earlier in their careers to discuss how the...

Real-time analysis of large-scale neuronal imaging enables closed-loop investigation of neural dynamics

by Clinical Neuropsychologist Online | Monday, March 11, 2024 | Neuroscience

Nature Neuroscience, Published online: 11 March 2024; doi:10.1038/s41593-024-01595-6A real-time analysis system was developed for an up to 500-megabyte-per-second image stream. This system can extract activities from up to 100,000 neurons in larval zebrafish brains...

The kainate receptor GluK2 mediates cold sensing in mice

by Clinical Neuropsychologist Online | Monday, March 11, 2024 | Neuroscience

Nature Neuroscience, Published online: 11 March 2024; doi:10.1038/s41593-024-01585-8The identity of receptors sensing cold temperatures in peripheral somatosensory neurons remains obscure. Cai et al. report that GluK2, a kainate receptor mediating synaptic...
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