by Clinical Neuropsychologist Online | Monday, April 22, 2024 | Dementia
Abstract INTRODUCTION We examined the efficacy of a multidomain intervention in preventing cognitive decline among Japanese older adults with mild cognitive impairment (MCI). METHODS Participants aged 65-85 years with MCI were randomized into intervention (management...
by Clinical Neuropsychologist Online | Monday, April 22, 2024 | Dementia
Abstract INTRODUCTION We investigate pathological correlates of plasma phosphorylated tau 181 (p-tau181), glial fibrillary acidic protein (GFAP), and neurofilament light chain (NfL) across a clinically diverse spectrum of neurodegenerative disease, including normal...
by Clinical Neuropsychologist Online | Monday, April 22, 2024 | Dementia
Abstract BACKGROUND Cortical microinfarcts (CMI) were attributed to cerebrovascular disease and cerebral amyloid angiopathy (CAA). CAA is frequent in Down syndrome (DS) while hypertension is rare, yet no studies have assessed CMI in DS. METHODS We included 195 adults...
by Clinical Neuropsychologist Online | Monday, April 22, 2024 | Neurorehabilitation
Rehabilitation Psychology, Vol 70(1), Feb 2025, 46-54; doi:10.1037/rep0000560Purpose: Effective pain management is vital for hip fracture recovery, yet the factors influencing pain reporting and pain medication use during inpatient rehabilitation for hip fractures are...
by Clinical Neuropsychologist Online | Monday, April 22, 2024 | Neuroscience
Nature Neuroscience, Published online: 22 April 2024; doi:10.1038/s41593-024-01624-4Gene expression in the human cortex is shown to involve three general components, which reflect metabolic and immune programs of healthy development, and link case–control imaging and...