by Clinical Neuropsychologist Online | Wednesday, September 30, 2026 | Dementia
Abstract INTRODUCTION Environmental exposures contribute substantially to Alzheimer’s disease and related dementias (ADRD), yet comprehensive exposome-wide investigations systematically evaluating multi-domain environmental factors remain limited and lacking...
by Clinical Neuropsychologist Online | Tuesday, September 29, 2026 | Dementia
Dementia, Ahead of Print. In the context of global demographic change, the number of patients with Alzheimer’s disease (AD) and other forms of dementia is steadily increasing. These individuals require ongoing care but often struggle to communicate their needs and...
by Clinical Neuropsychologist Online | Monday, September 28, 2026 | Dementia
Abstract External exposome research offers opportunities to evaluate complex relationships between multiple environmental determinants of Alzheimer’s disease and related dementias (ADRD). However, selecting specific exposure domains, identifying metrics, and...
by Clinical Neuropsychologist Online | Monday, September 28, 2026 | Dementia
Abstract BACKGROUND The APOE ε4 allele has weaker association with ADRD outcomes in Hispanic/Latino populations compared to non-Hispanic White and East Asian populations. METHODS We used whole-genome sequencing data from 13,025 Hispanic/Latino adults to infer...
by Clinical Neuropsychologist Online | Monday, September 28, 2026 | Dementia
Abstract INTRODUCTION Dysregulated cholesterol metabolism represents a critical metabolic stressor in the central nervous system, contributing to neuronal injury across multiple neurological conditions, including Alzheimer’s disease (AD). While glucagon-like...
by Clinical Neuropsychologist Online | Monday, September 28, 2026 | Dementia
Abstract Since the groundbreaking work of Alois Alzheimer in the early 1900s, Alzheimer’s disease research has evolved immensely, most notably with the establishment of the Alzheimer’s Disease Research Centers (ADRC). Fueled by the vision and funding of...
