A single-cell mass cytometry-based atlas of the developing mouse brain

by Clinical Neuropsychologist | Wednesday, December 18, 2024 | Neuroscience

Nature Neuroscience, Published online: 18 December 2024; doi:10.1038/s41593-024-01786-1In recent years, valuable mRNA-based developmental atlases of the mouse brain have been made available. Here, the authors use single-cell mass cytometry to build a protein-based...

Creating a Blueprint for Sleep Engineering 

by Clinical Neuropsychologist | Wednesday, December 18, 2024 | Neuroscience

CNS 2025: Q&A with Ken Paller What started for Ken Paller as traditional memory research in cognitive neuroscience has now turned into an integrated approach to understanding memory, sleep, and dreams. In addition to using novel tools and technologies to modify...

Heat acclimation induces hypothalamic temperature sensitivity that promotes heat tolerance

by Clinical Neuropsychologist | Tuesday, December 17, 2024 | Neuroscience

Nature Neuroscience, Published online: 17 December 2024; doi:10.1038/s41593-024-01835-9After long-term heat exposure, a discrete group of hypothalamic neurons in the anterior ventromedial preoptic area become hyperactive and acquire temperature sensitivity. This...

MeCP2 goes into unmethylated territories

by Clinical Neuropsychologist | Tuesday, December 17, 2024 | Neuroscience

Nature Neuroscience, Published online: 17 December 2024; doi:10.1038/s41593-024-01846-6Methyl-CpG-binding protein 2 (MeCP2) is a chromatin regulator whose loss of function causes Rett syndrome. It has been unclear how the gene-expression changes caused by loss of...

Author Correction: Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery

by Clinical Neuropsychologist | Monday, December 16, 2024 | Neuroscience

Nature Neuroscience, Published online: 16 December 2024; doi:10.1038/s41593-024-01858-2Author Correction: Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery If you do not see content above, kindly GO TO...

Amygdala intercalated cells form an evolutionarily conserved system orchestrating brain networks

by Clinical Neuropsychologist | Friday, December 13, 2024 | Neuroscience

Nature Neuroscience, Published online: 13 December 2024; doi:10.1038/s41593-024-01836-8This comprehensive review of amygdala intercalated cells (ITCs) proposes a revised model of ITCs as a highly coordinated system that integrates diverse inputs to orchestrate...