by Clinical Neuropsychologist Online | Friday, August 30, 2024 | Dementia
Abstract INTRODUCTION Alzheimer’s disease (AD) disproportionately affects minoritized populations who remain underrepresented in AD trials. METHODS We partnered with local nursing community-based organizations to implement a culturally tailored educational...
by Clinical Neuropsychologist Online | Thursday, August 29, 2024 | Dementia
Abstract Many coronavirus disease 2019 (COVID-19) positive individuals exhibit abnormal electroencephalographic (EEG) activity reflecting “brain fog” and mild cognitive impairments even months after the acute phase of infection. Resting-state EEG abnormalities include...
by Clinical Neuropsychologist Online | Wednesday, August 28, 2024 | Dementia
Abstract INTRODUCTION We investigated blood DNA methylation patterns associated with 15 well-established cerebrospinal fluid (CSF) biomarkers of Alzheimer’s disease (AD) pathophysiology, neuroinflammation, and neurodegeneration. METHODS We assessed DNA...
by Clinical Neuropsychologist Online | Wednesday, August 28, 2024 | Dementia
Abstract INTRODUCTION The established link between DNA methylation and pathophysiology of dementia, along with its potential role as a molecular mediator of lifestyle and environmental influences, positions blood-derived DNA methylation as a promising tool for early...
by Clinical Neuropsychologist Online | Wednesday, August 28, 2024 | Dementia
Abstract INTRODUCTION Typical Alzheimer’s disease (AD) and limbic-predominant age-related TAR DNA-binding protein 43 (TDP-43) encephalopathy (LATE) are two neurodegenerative diseases that present with a similar initial amnestic clinical phenotype but are...