by Clinical Neuropsychologist | Wednesday, June 19, 2024 | Dementia
Abstract INTRODUCTION Despite prior research on the association between sarcopenia and cognitive impairment in the elderly, a comprehensive model that integrates various brain pathologies is still lacking. METHODS We used data from 528 non-demented older adults with...
by Clinical Neuropsychologist | Tuesday, June 18, 2024 | Dementia
Dementia, Volume 23, Issue 6, Page 1021-1035, August 2024. Objectives: This study aimed to understand the care needs, care arrangements and burden of care for people with dementia in Northern Tanzania. Methods: This was a cross-sectional, observational study. People...
by Clinical Neuropsychologist | Tuesday, June 18, 2024 | Dementia
Abstract INTRODUCTION Corticobasal syndrome (CBS) can result from underlying Alzheimer’s disease (AD) pathologies. Little is known about the utility of blood plasma metrics to predict positron emission tomography (PET) biomarker-confirmed AD in CBS. METHODS A...
by Clinical Neuropsychologist | Monday, June 17, 2024 | Dementia
Abstract INTRODUCTION Tau aggregation into neurofibrillary tangles in Alzheimer’s disease (AD) is a dynamic process involving changes in tau phosphorylation, isoform composition, and morphology. To facilitate studies of tangle maturity, we developed an image...
by Clinical Neuropsychologist | Monday, June 17, 2024 | Dementia
Abstract INTRODUCTION Intraneuronal inclusions composed of tau protein are found in Alzheimer’s disease (AD) and other tauopathies. Tau normally binds microtubules (MTs), and its disengagement from MTs and misfolding in AD is thought to result in MT...
