by Clinical Neuropsychologist | Saturday, July 6, 2024 | Dementia
Abstract BACKGROUND We investigated the association of peak expiratory flow (PEF) with dementia; cognitive impairment, no dementia (CIND); and transition from CIND to dementia, and possible underlying neuropathological mechanisms. METHODS A population-based cohort of...
by Clinical Neuropsychologist | Friday, July 5, 2024 | Dementia
Abstract INTRODUCTION Microtubule (MT) stability is crucial for proper neuronal function. Understanding MT dysregulation is critical for connecting amyloid beta (Aβ) and tau-based degenerative events and early changes in presymptomatic Alzheimer’s disease (AD)....
by Clinical Neuropsychologist | Friday, July 5, 2024 | Dementia
Abstract INTRODUCTION Dementia risk scores constitute promising surrogate outcomes for lifestyle interventions targeting cognitive function. We investigated whether dementia risk, assessed using the LIfestyle for BRAin health (LIBRA) index, was reduced by the...
by Clinical Neuropsychologist | Friday, July 5, 2024 | Dementia
Abstract Sex and gender—biological and social constructs—significantly impact the prevalence of protective and risk factors, influencing the burden of Alzheimer’s disease (AD; amyloid beta and tau) and other pathologies (e.g., cerebrovascular disease) which...
by Clinical Neuropsychologist | Thursday, July 4, 2024 | Dementia
Abstract INTRODUCTION Although poor glycemic control is associated with dementia, it is unknown if variability in glycemic control, even in those with optimal glycosylated hemoglobin A1c (HbA1c) levels, increases dementia risk. METHODS Among 171,964 people with type 2...
