by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Dementia
Abstract INTRODUCTION We discovered that the APOE3 Christchurch (APOE3Ch) variant may provide resistance to Alzheimer’s disease (AD). This resistance may be due to reduced pathological interactions between ApoE3Ch and heparan sulfate proteoglycans (HSPGs)....
by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Dementia
Abstract INTRODUCTION The U.S. study to protect brain health through lifestyle intervention to reduce risk (U.S. POINTER) is conducted to confirm and expand the results of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)...
by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Dementia
Abstract INTRODUCTION Verbal fluency tasks are common in Alzheimer’s disease (AD) assessments. Yet, standard valid response counts fail to reveal disease-specific semantic memory patterns. Here, we leveraged automated word-property analysis to capture...
by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Dementia
Abstract INTRODUCTION The results of the CLARITY-AD, GRADUATE I and II, and TRAILBLAZER-ALZ 2 trials have rekindled discussion on the impact of amyloid-targeting drugs. We use a Bayesian approach to quantify how rational observers would have updated their prior...
by Clinical Neuropsychologist Online | Wednesday, February 21, 2024 | Dementia
Dementia, Volume 23, Issue 6, Page 907-926, August 2024. Many people living with dementia have difficulties at mealtimes, which can result in serious complications for physical and mental health, leading to hospital admissions and even death. However, current training...
