by Clinical Neuropsychologist Online | Monday, September 28, 2026 | Dementia
Abstract External exposome research offers opportunities to evaluate complex relationships between multiple environmental determinants of Alzheimer’s disease and related dementias (ADRD). However, selecting specific exposure domains, identifying metrics, and...
by Clinical Neuropsychologist Online | Monday, September 28, 2026 | Dementia
Abstract BACKGROUND The APOE ε4 allele has weaker association with ADRD outcomes in Hispanic/Latino populations compared to non-Hispanic White and East Asian populations. METHODS We used whole-genome sequencing data from 13,025 Hispanic/Latino adults to infer...
by Clinical Neuropsychologist Online | Monday, September 28, 2026 | Dementia
Abstract INTRODUCTION Dysregulated cholesterol metabolism represents a critical metabolic stressor in the central nervous system, contributing to neuronal injury across multiple neurological conditions, including Alzheimer’s disease (AD). While glucagon-like...
by Clinical Neuropsychologist Online | Monday, September 28, 2026 | Dementia
Abstract Since the groundbreaking work of Alois Alzheimer in the early 1900s, Alzheimer’s disease research has evolved immensely, most notably with the establishment of the Alzheimer’s Disease Research Centers (ADRC). Fueled by the vision and funding of...
by Clinical Neuropsychologist Online | Monday, September 28, 2026 | Dementia
Abstract INTRODUCTION Plasma phosphorylated tau 217 (p‑tau217) immunoassays are increasingly being used to assess Alzheimer’s disease (AD) pathology despite limited data affirming test reliability over time. METHODS Clinical performance of the Fujirebio...
