by Clinical Neuropsychologist Online | Wednesday, August 12, 2026 | Dementia
Abstract INTRODUCTION Post mortem proteomic analysis of Alzheimer’s disease (AD) brain tissue has identified novel target genes and proteins for potential therapeutic development. Moesin (MSN) and CD44 were identified as candidate targets. Using human induced...
by Clinical Neuropsychologist Online | Wednesday, August 12, 2026 | Dementia
Dementia, Ahead of Print. Although approaches exist to address challenges in supporting participation of people living with dementia in research, these approaches are rarely evaluated, a critical step to understand their influence on promoting the engagement of people...
by Clinical Neuropsychologist Online | Tuesday, August 11, 2026 | Dementia
Abstract Obstructive sleep apnea (OSA), a common though underdiagnosed disorder in older adults, represents a potential upstream vascular stressor linked to increased Alzheimer’s disease (AD) risk. In this Perspective article, we propose a stage-informed...
by Clinical Neuropsychologist Online | Tuesday, August 11, 2026 | Dementia
Abstract Vascular-related factors are now considered major contributors to most forms of dementia, including Alzheimer’s disease. However, the degree to which vascular deficits contribute to risk, onset, and progression of cognitive impairment and dementia has...
by Clinical Neuropsychologist Online | Tuesday, August 11, 2026 | Dementia
Abstract INTRODUCTION Socioeconomic factors influence cognitive outcomes and may modify associations between neuropathologies and cognitive outcomes, yet evidence from low- and middle-income contexts remains scarce. METHODS We used harmonized data from nationally...
