by Clinical Neuropsychologist Online | Tuesday, September 15, 2026 | Dementia
Abstract INTRODUCTION We studied dementia incidence and risk factors in Indigenous Tsimane and Moseten Amerindian populations in Amazonian Bolivia with largely subsistence lifestyles. METHODS A median of 4.7 years after baseline dementia assessment, 730 participants...
by Clinical Neuropsychologist Online | Tuesday, September 15, 2026 | Dementia
Abstract INTRODUCTION Lysosomal dysfunction contributes to Alzheimer’s disease (AD) by impairing protein clearance and promoting neuroinflammation. Cathepsin H (CTSH), a lysosomal protease, recently emerged as a protective AD locus. We investigated how CTSH is...
by Clinical Neuropsychologist Online | Tuesday, September 15, 2026 | Dementia
Abstract INTRODUCTION Amyloid positivity does not reliably predict near-term cognitive decline in preclinical Alzheimer’s disease (AD). We tested whether digital cognitive phenotyping improves prognostic precision. METHODS Baseline performance on a brief...
by Clinical Neuropsychologist Online | Tuesday, September 15, 2026 | Dementia
Abstract As cardiac surgery becomes more common, concerns about postoperative cognitive decline and the potential progression to dementia have grown. While postoperative cognitive dysfunction (POCD) is well documented, its relationship to long-term dementia risk...
by Clinical Neuropsychologist Online | Tuesday, September 15, 2026 | Dementia
Abstract INTRODUCTION Our goal was to determine Alzheimer’s disease (AD) and related dementias (ADRD) incidence and risk factors among American Indian and Alaska Native (AI/AN) veterans, an understudied group. METHODS We identified AI/AN veterans ≥ 55 years...
