by Clinical Neuropsychologist Online | Wednesday, September 9, 2026 | Dementia
Abstract BACKGROUND Sleep phenotypes differ in progressive supranuclear palsy (PSP) and Alzheimer’s disease (AD). The human intermediate nucleus (IntN), a putative ventrolateral preoptic analog, promotes non-rapid eye movement (NREM) sleep, but its...
by Clinical Neuropsychologist Online | Wednesday, September 9, 2026 | Dementia
Abstract INTRODUCTION Diffusion tensor image analysis along the perivascular space (DTI-ALPS) index is associated with neurodegenerative diseases (NDDs), but its shared genetic basis with NDDs remains unclear. METHODS By integrating genome-wide association datasets...
by Clinical Neuropsychologist Online | Wednesday, September 9, 2026 | Dementia
Abstract INTRODUCTION Latinos face increased Alzheimer’s disease (AD) risk but are underrepresented in studies of APOE genotype disclosure. We evaluated the psychological impacts of APOE disclosure in the Información de la Enfermedad de Alzheimer para Latinos...
by Clinical Neuropsychologist Online | Tuesday, September 8, 2026 | Dementia
Abstract INTRODUCTION Locus coeruleus (LC) and glymphatic dysfunction have been linked both to Alzheimer’s disease (AD) and, recently, to infraslow oscillation (ISO) in sleep spindle (sigma) activity (ISO). Here we hypothesize ISO integrity is a critical link...
by Clinical Neuropsychologist Online | Tuesday, September 8, 2026 | Dementia
Abstract INTRODUCTION A higher incidence of dementia, including Alzheimer’s-like pathology, is observed in aged people living with human immunodeficiency virus-1 (HIV-1). However, mechanisms linking HIV-1 to Alzheimer’s disease (AD) pathology remain...