by Clinical Neuropsychologist | Monday, February 24, 2025 | Dementia
Abstract INTRODUCTION Physical activity is associated with greater myelin content in older individuals with cerebral small vessel disease (CSVD), a condition marked by demyelination. However, potential mechanisms underlying this relationship remain understudied....
by Clinical Neuropsychologist | Monday, February 24, 2025 | Dementia
Abstract INTRODUCTION Positron emission tomography (PET) imaging studies have shown that amyloid beta (Aβ) is significantly correlated with glucose metabolism in mild cognitive impairment independently of the apolipoprotein E (APOE) ε4 genotype. METHODS We used a...
by Clinical Neuropsychologist | Monday, February 24, 2025 | Dementia
Abstract INTRODUCTION Few studies have characterized the association of olfaction with dementia in detail across diverse sociodemographic subgroups. METHODS We examined the association of one-time-point olfactory status with incident dementia overall and by age, race,...
by Clinical Neuropsychologist | Monday, February 24, 2025 | Dementia
Abstract INTRODUCTION Dual cognitive and mobility decline is more strongly associated with dementia risk than cognitive decline only. It remains unknown whether this syndrome is associated with brain atrophy patterns, white matter (WM) damage, or pathology. METHODS In...
by Clinical Neuropsychologist | Monday, February 24, 2025 | Dementia
Abstract INTRODUCTION The long-term implications of disclosing Alzheimer’s disease (AD) biomarker information to cognitively unimpaired individuals are unknown. METHODS We compared participants who disclosed their elevated amyloid imaging result in a preclinical...
