by Clinical Neuropsychologist | Thursday, July 11, 2024 | Dementia
Abstract INTRODUCTION Spatial extent-based measures of how far amyloid beta (Aβ) has spread throughout the neocortex may be more sensitive than traditional Aβ-positron emission tomography (PET) measures of Aβ level for detecting early Aβ deposits in preclinical...
by Clinical Neuropsychologist | Thursday, July 11, 2024 | Dementia
Abstract INTRODUCTION Older Black adults are at risk of cerebral small vessel disease (CSVD), which contributes to dementia risk. Two subtypes of CSVD, arteriolosclerosis and ischemic lacunar infarcts, have been independently linked to lower cognition and higher...
by Clinical Neuropsychologist | Wednesday, July 10, 2024 | Dementia
Abstract INTRODUCTION Higher neuroticism might be associated with dementia risk. Here we investigated modification by genetic predisposition to dementia, mediation by mental health and vascular conditions, neuroimaging outcomes, and cognitive function. METHODS Cox...
by Clinical Neuropsychologist | Wednesday, July 10, 2024 | Dementia
Abstract INTRODUCTION Substantial racial and ethnic disparities in hypertension and dementia exist in the United States. We evaluated the effect of maintaining systolic blood pressure (SBP) below clinical thresholds on dementia incidence. METHODS We included 6806...
by Clinical Neuropsychologist | Wednesday, July 10, 2024 | Dementia
Abstract BACKGROUND Previous studies have found that Alzheimer’s disease (AD)-related plasma markers are associated with amyloid beta (Aβ) deposition, but the change of this association in different Aβ pathological stages remains unclear. METHODS Data were...
