by Clinical Neuropsychologist Online | Monday, February 24, 2025 | Dementia
Abstract INTRODUCTION Dual cognitive and mobility decline is more strongly associated with dementia risk than cognitive decline only. It remains unknown whether this syndrome is associated with brain atrophy patterns, white matter (WM) damage, or pathology. METHODS In...
by Clinical Neuropsychologist Online | Monday, February 24, 2025 | Dementia
Abstract INTRODUCTION The long-term implications of disclosing Alzheimer’s disease (AD) biomarker information to cognitively unimpaired individuals are unknown. METHODS We compared participants who disclosed their elevated amyloid imaging result in a preclinical...
by Clinical Neuropsychologist Online | Monday, February 24, 2025 | Dementia
Abstract INTRODUCTION Early symptoms in young onset Alzheimer’s disease (YOAD) may be misinterpreted, causing delayed diagnosis. This population-based study aimed to map adverse occupational events preceding YOAD diagnosis as potential prodromal signs. METHODS...
by Clinical Neuropsychologist Online | Monday, February 24, 2025 | Dementia
Abstract INTRODUCTION We investigated the moderating effects of midlife and late-life cognitive activity (CA) on the relationship between tau pathology and both cognition and cognitive decline. METHODS Eighty-nine non-demented older adults from a Korean cohort...
by Clinical Neuropsychologist Online | Saturday, February 22, 2025 | Dementia
Abstract INTRODUCTION Isolated REM sleep behavior disorder (iRBD) is a strong prodromal marker of Lewy body diseases (LBDs) – Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). Cholinergic loss is linked to cognitive decline in these conditions, but...
