by Clinical Neuropsychologist | Sunday, October 6, 2024 | Dementia
Abstract INTRODUCTION Nursing home (NH) residents with Alzheimer’s disease or related dementias (ADRD) are at high risk for hospital transfer. We aimed to (1) describe characteristics and predictors of avoidable transfer of residents with ADRD and (2) explore...
by Clinical Neuropsychologist | Sunday, October 6, 2024 | Dementia
Abstract INTRODUCTION Growing evidence suggests a role for neuroinflammation in Alzheimer’s disease (AD). We investigated complement pathway activity in AD patient cerebrospinal fluid (CSF) and evaluated its modulation by the anti-tau antibody semorinemab....
by Clinical Neuropsychologist | Sunday, October 6, 2024 | Dementia
Abstract A brief history of events surrounding the conceptualization and original implementation of the Alzheimer’s Disease Neuroimaging Initiative (ADNI) as a public–private partnership (PPP) is provided from the perspective of three individuals directly...
by Clinical Neuropsychologist | Sunday, October 6, 2024 | Dementia
Abstract Diagnosing Alzheimer’s disease (AD) poses significant challenges to health care, often resulting in delayed or inadequate patient care. The clinical integration of blood-based biomarkers (BBMs) for AD holds promise in enabling early detection of...
by Clinical Neuropsychologist | Sunday, October 6, 2024 | Dementia
Abstract INTRODUCTION We evaluated the efficacy and safety of brexpiprazole for the treatment of agitation in Alzheimer’s dementia (AAD) in Japanese patients. METHODS This was a phase 2/3 multicenter, randomized, double-blind, placebo-controlled, parallel-group...
