by Clinical Neuropsychologist | Tuesday, May 27, 2025 | Neuroscience
Nature Neuroscience, Published online: 27 May 2025; doi:10.1038/s41593-025-01979-2The microglia–neuron interactions contributing to neuronal hyperexcitability are unclear. Here, the authors show how GABA and C3 signaling coordinate microglial engulfment of inhibitory...
by Clinical Neuropsychologist | Tuesday, May 27, 2025 | Neuroscience
Nature Neuroscience, Published online: 27 May 2025; doi:10.1038/s41593-025-01966-7Parhizkar et al. show that lemborexant, an orexin receptor antagonist, protects against neurodegeneration in male tau transgenic mice by preventing tau protein build-up and inflammation,...
by Clinical Neuropsychologist | Monday, May 26, 2025 | Neuroscience
Nature Neuroscience, Published online: 26 May 2025; doi:10.1038/s41593-025-01964-9Rogers et al. show that psilocybin enhances fear extinction, suppresses fear neurons and recruits extinction neurons in the retrosplenial cortex in mice, providing evidence that its...
by Clinical Neuropsychologist | Thursday, May 22, 2025 | Neuroscience
Nature Neuroscience, Published online: 22 May 2025; doi:10.1038/s41593-025-01955-wWhite matter aging leads to degenerative and inflammatory changes. Here the authors show that microglial dysfunction exacerbates glial CXCL10 expression, harmful CD8+ T cell recruitment,...
by Clinical Neuropsychologist | Thursday, May 22, 2025 | Neuroscience
Nature Neuroscience, Published online: 22 May 2025; doi:10.1038/s41593-025-01929-yAging induces pathological changes in central nervous system (CNS) myelin, which in turn induce microglia dysregulation. What is the consequence of this microglial response on white...
