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Dorsoventral hippocampus neural assemblies reactivate during sleep following an aversive experience

by Clinical Neuropsychologist Online | Wednesday, April 1, 2026 | Neuroscience

Nature Neuroscience, Published online: 01 April 2026; doi:10.1038/s41593-026-02252-wSynchronization of sharp-wave ripples across the dorsoventral hippocampus during sleep supports coordinated reactivation that represents negative experiences more faithfully than...

Entorhinal cortex represents task-relevant remote locations independently of CA1

by Clinical Neuropsychologist Online | Wednesday, April 1, 2026 | Neuroscience

Nature Neuroscience, Published online: 01 April 2026; doi:10.1038/s41593-026-02232-0Neurons in medial entorhinal cortex collectively represent discrete nonlocal positions during immobility. During this nonlocal coding, CA1 is uncoupled from entorhinal cortex. These...

Neuropeptide Y co-opts neuronal ensembles for memory lability and stability

by Clinical Neuropsychologist Online | Tuesday, March 31, 2026 | Neuroscience

Nature Neuroscience, Published online: 31 March 2026; doi:10.1038/s41593-026-02235-xThis study from Wei-Guang Li, Tian-Le Xu and colleagues shows that neuropeptide Y released by specific hippocampal inhibitory neurons can switch fear memories into extinction memories...

Null models for lesion network mapping

by Clinical Neuropsychologist Online | Monday, March 30, 2026 | Neuroscience

Nature Neuroscience, Published online: 30 March 2026; doi:10.1038/s41593-026-02259-3Van den Heuvel et al. show that lesion-network mapping (LNM)-derived circuits converge across disorders and argue that this convergence reflects a fundamental methodological limitation...

Neuroimmune interferon signals sustain arthritis pain

by Clinical Neuropsychologist Online | Monday, March 30, 2026 | Neuroscience

Nature Neuroscience, Published online: 30 March 2026; doi:10.1038/s41593-026-02251-xPain in rheumatoid arthritis often persists independently of joint inflammation. In this issue, Su et al. demonstrate that sustained non-canonical type 1 interferon signaling within...
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